MiR-122-5p and miR-326-3p promote cadmium-induced NRK-52E cell apoptosis by downregulating PLD1.

Yuan, Wenya; Liang, Lixia; Huang, Ke; Deng, Yaotang; Dong, Ming; Wang, Guanghai; Zou, Fei

Yuan, Wenya; Liang, Lixia; Huang, Ke; Deng, Yaotang; Dong, Ming; Wang, Guanghai; Zou, Fei.

Afiliación

Yuan W; Department of Occupational Health and Occupational Medicine, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, China.
Liang L; Department of Occupational Health and Occupational Medicine, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, China.
Huang K; Department of Occupational Health and Occupational Medicine, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, China.
Deng Y; Department of Occupational Health and Occupational Medicine, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, China.
Dong M; Guangdong Provincial Key Laboratory of Occupational Disease Prevention and Treatment, Guangdong Province Hospital for Occupational Disease Prevention and Treatment, Guangzhou, China.
Wang G; Department of Occupational Health and Occupational Medicine, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, China.
Zou F; Department of Occupational Health and Occupational Medicine, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, China.

Environ Toxicol ; 35(12): 1334-1342, 2020 Dec.

Article en En | MEDLINE | ID: mdl-32697411

Asunto(s)

Apoptosis/efectos de los fármacos; Cadmio/toxicidad; Células Epiteliales/efectos de los fármacos; MicroARNs/genética; Fosfolipasa D/genética; Regiones no Traducidas 3'; Animales; Apoptosis/genética; Línea Celular; Proliferación Celular/efectos de los fármacos; Proliferación Celular/genética; Relación Dosis-Respuesta a Droga; Regulación hacia Abajo; Células Epiteliales/metabolismo; Células Epiteliales/patología; Regulación de la Expresión Génica/efectos de los fármacos; Humanos; Riñón/efectos de los fármacos; Riñón/metabolismo; Riñón/patología; Masculino; Ratas; Ratas Sprague-Dawley

Palabras clave

PLD1; apoptosis; cadmium; kidney; miR-122-5p; miR-326-3p

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Fosfolipasa D / Cadmio / Apoptosis / MicroARNs / Células Epiteliales Límite: Animals / Humans / Male Idioma: En Revista: Environ Toxicol Asunto de la revista: SAUDE AMBIENTAL / TOXICOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: China

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