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HATK: HLA analysis toolkit.
Choi, Wanson; Luo, Yang; Raychaudhuri, Soumya; Han, Buhm.
Afiliación
  • Choi W; Department of Biomedical Sciences, BK21 Plus Biomedical Science Project, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.
  • Luo Y; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Raychaudhuri S; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Han B; Center for Data Sciences, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Bioinformatics ; 37(3): 416-418, 2021 04 20.
Article en En | MEDLINE | ID: mdl-32735319
ABSTRACT

SUMMARY:

Fine-mapping human leukocyte antigen (HLA) genes involved in disease susceptibility to individual alleles or amino acid residues has been challenging. Using information regarding HLA alleles obtained from HLA typing, HLA imputation or HLA inference, our software expands the alleles to amino acid sequences using the most recent IMGT/HLA database and prepares a dataset suitable for fine-mapping analysis. Our software also provides useful functionalities, such as various association tests, visualization tools and nomenclature conversion. AVAILABILITY AND IMPLEMENTATION https//github.com/WansonChoi/HATK.
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Programas Informáticos / Antígenos HLA Límite: Humans Idioma: En Revista: Bioinformatics Asunto de la revista: INFORMATICA MEDICA Año: 2021 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Programas Informáticos / Antígenos HLA Límite: Humans Idioma: En Revista: Bioinformatics Asunto de la revista: INFORMATICA MEDICA Año: 2021 Tipo del documento: Article