Deltex-1 is indispensible for the IL-6 and TGF-ß treatment-triggered differentiation of Th17 cells.

Tang, Zhengle; Wang, Yuan; Xing, Rui; Zeng, Shan; Di, Jingfang; Xing, Feiyue

Tang, Zhengle; Wang, Yuan; Xing, Rui; Zeng, Shan; Di, Jingfang; Xing, Feiyue.

Afiliación

Tang Z; Institute of Tissue Transplantation and Immunology, Department of Immunobiology, Jinan University, Guangzhou 510632, China; MOE Key Laboratory of Tumor Molecular Biology, Key Laboratory of Functional Protein Research of Guangdong, Higher Education Institutes, Jinan University, Guangzhou 510632, Chin
Wang Y; Institute of Tissue Transplantation and Immunology, Department of Immunobiology, Jinan University, Guangzhou 510632, China.
Xing R; Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China; MOE Key Laboratory of Protein Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China.
Zeng S; Institute of Tissue Transplantation and Immunology, Department of Immunobiology, Jinan University, Guangzhou 510632, China.
Di J; Institute of Tissue Transplantation and Immunology, Department of Immunobiology, Jinan University, Guangzhou 510632, China.
Xing F; Institute of Tissue Transplantation and Immunology, Department of Immunobiology, Jinan University, Guangzhou 510632, China; MOE Key Laboratory of Tumor Molecular Biology, Key Laboratory of Functional Protein Research of Guangdong, Higher Education Institutes, Jinan University, Guangzhou 510632, Chin

Cell Immunol ; 356: 104176, 2020 10.

Article en En | MEDLINE | ID: mdl-32736174

Asunto(s)

Diferenciación Celular/fisiología; Ubiquitina-Proteína Ligasas/metabolismo; Animales; Linfocitos T CD4-Positivos/metabolismo; Citocinas/metabolismo; Factores de Transcripción Forkhead/metabolismo; Regulación de la Expresión Génica/efectos de los fármacos; Interleucina-6/metabolismo; Masculino; Ratones; Ratones Endogámicos BALB C; Miembro 3 del Grupo F de la Subfamilia 1 de Receptores Nucleares/inmunología; Miembro 3 del Grupo F de la Subfamilia 1 de Receptores Nucleares/metabolismo; Transducción de Señal/efectos de los fármacos; Células Th17/metabolismo; Factor de Crecimiento Transformador beta/metabolismo; Ubiquitina-Proteína Ligasas/inmunología

Palabras clave

Deltex-1; Differentiation; RORÎ³t; Regulation; Th17

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Diferenciación Celular / Ubiquitina-Proteína Ligasas Límite: Animals Idioma: En Revista: Cell Immunol Año: 2020 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google