Chronic genotype 1 hepatitis C along with cirrhosis drives a persistent imprint in virus-specific CD8<sup>+</sup> T cells after direct-acting antiviral therapies.

Perpiñán, Elena; Pérez-Del-Pulgar, Sofía; Londoño, María-Carlota; Mariño, Zoe; Lens, Sabela; Leonel, Thais; Bartres, Concepción; García-López, Mireia; Rodriguez-Tajes, Sergio; Forns, Xavier; Koutsoudakis, George

Chronic genotype 1 hepatitis C along with cirrhosis drives a persistent imprint in virus-specific CD8⁺ T cells after direct-acting antiviral therapies.

Perpiñán, Elena; Pérez-Del-Pulgar, Sofía; Londoño, María-Carlota; Mariño, Zoe; Lens, Sabela; Leonel, Thais; Bartres, Concepción; García-López, Mireia; Rodriguez-Tajes, Sergio; Forns, Xavier; Koutsoudakis, George.

Afiliación

Perpiñán E; Liver Unit, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERehd, Barcelona, Spain.
Pérez-Del-Pulgar S; Liver Unit, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERehd, Barcelona, Spain.
Londoño MC; Liver Unit, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERehd, Barcelona, Spain.
Mariño Z; Liver Unit, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERehd, Barcelona, Spain.
Lens S; Liver Unit, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERehd, Barcelona, Spain.
Leonel T; Liver Unit, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERehd, Barcelona, Spain.
Bartres C; Liver Unit, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERehd, Barcelona, Spain.
García-López M; Liver Unit, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERehd, Barcelona, Spain.
Rodriguez-Tajes S; Liver Unit, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERehd, Barcelona, Spain.
Forns X; Liver Unit, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERehd, Barcelona, Spain.
Koutsoudakis G; Liver Unit, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERehd, Barcelona, Spain.

J Viral Hepat ; 27(12): 1408-1418, 2020 12.

Article en En | MEDLINE | ID: mdl-32812325

Asunto(s)

Hepatitis C Crónica; Hepatitis C; Antivirales/uso terapéutico; Linfocitos T CD8-positivos; Genotipo; Hepacivirus; Hepatitis C/tratamiento farmacológico; Hepatitis C Crónica/complicaciones; Hepatitis C Crónica/tratamiento farmacológico; Humanos; Cirrosis Hepática/tratamiento farmacológico

Palabras clave

T-cell restoration; cirrhosis; direct-acting antivirals; hepatitis C virus; virus-specific CD8+ T cells

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Hepatitis C / Hepatitis C Crónica Límite: Humans Idioma: En Revista: J Viral Hepat Asunto de la revista: GASTROENTEROLOGIA Año: 2020 Tipo del documento: Article País de afiliación: España

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