Improving the Stability of Maleimide-Thiol Conjugation for Drug Targeting.

Lahnsteiner, Marianne; Kastner, Alexander; Mayr, Josef; Roller, Alexander; Keppler, Bernhard K; Kowol, Christian R

Lahnsteiner, Marianne; Kastner, Alexander; Mayr, Josef; Roller, Alexander; Keppler, Bernhard K; Kowol, Christian R.

Afiliación

Lahnsteiner M; Faculty of Chemistry, Institute of Inorganic Chemistry, University of Vienna, Waehringer Strasse 42, 1090, Vienna, Austria.
Kastner A; Faculty of Chemistry, Institute of Inorganic Chemistry, University of Vienna, Waehringer Strasse 42, 1090, Vienna, Austria.
Mayr J; Faculty of Chemistry, Institute of Inorganic Chemistry, University of Vienna, Waehringer Strasse 42, 1090, Vienna, Austria.
Roller A; Faculty of Chemistry, Institute of Inorganic Chemistry, University of Vienna, Waehringer Strasse 42, 1090, Vienna, Austria.
Keppler BK; Faculty of Chemistry, Institute of Inorganic Chemistry, University of Vienna, Waehringer Strasse 42, 1090, Vienna, Austria.
Kowol CR; Research Cluster "Translational Cancer Therapy Research", Waehringer Strasse 42, 1090, Vienna, Austria.

Chemistry ; 26(68): 15867-15870, 2020 Dec 04.

Article en En | MEDLINE | ID: mdl-32871016

Asunto(s)

Inmunoconjugados; Maleimidas; Compuestos de Sulfhidrilo; Ciclización; Sistemas de Liberación de Medicamentos; Estabilidad de Medicamentos; Inmunoconjugados/química; Maleimidas/química; Succinimidas/química; Compuestos de Sulfhidrilo/química

Palabras clave

bioconjugation; bioorganic chemistry; drug delivery; maleimide; retro-Michael reactions

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Compuestos de Sulfhidrilo / Inmunoconjugados / Maleimidas Idioma: En Revista: Chemistry Asunto de la revista: QUIMICA Año: 2020 Tipo del documento: Article País de afiliación: Austria

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