Generation of α-Boryl Radicals and Their Conjugate Addition to Enones: Transition-Metal-Free Alkylation of gem-Diborylalkanes.
Chemistry
; 27(7): 2294-2298, 2021 Feb 01.
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| MEDLINE
| ID: mdl-33064327
ABSTRACT
A transition-metal-free method for the alkylation of gem-diborylalkanes with α,ß-unsaturated ketones has been developed. It is demonstrated that the α-boryl radicals can be generated efficiently from gem-diborylalkanes with the aid of catechol and oxidants. The α-boryl radicals formed through such process can be engaged in conjugate addition reaction with α,ß-unsaturated ketones. This transformation is a straightforward method for the synthesis of γ-borylketones.
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MEDLINE
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En
Revista:
Chemistry
Asunto de la revista:
QUIMICA
Año:
2021
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Article