Short-chain fatty acid butyrate, a breast milk metabolite, enhances immature intestinal barrier function genes in response to inflammation in vitro and in vivo.

Gao, Yanan; Davis, Brittany; Zhu, Weishu; Zheng, Nan; Meng, Di; Walker, W Allan

Gao, Yanan; Davis, Brittany; Zhu, Weishu; Zheng, Nan; Meng, Di; Walker, W Allan.

Afiliación

Gao Y; State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, Peoples Republic of China.
Davis B; Mucosal Immunology and Biology Research Center, Massachusetts General Hospital for Children, Harvard Medical School, Boston, Massachusetts.
Zhu W; Mucosal Immunology and Biology Research Center, Massachusetts General Hospital for Children, Harvard Medical School, Boston, Massachusetts.
Zheng N; State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, Peoples Republic of China.
Meng D; Mucosal Immunology and Biology Research Center, Massachusetts General Hospital for Children, Harvard Medical School, Boston, Massachusetts.
Walker WA; Mucosal Immunology and Biology Research Center, Massachusetts General Hospital for Children, Harvard Medical School, Boston, Massachusetts.

Am J Physiol Gastrointest Liver Physiol ; 320(4): G521-G530, 2021 04 01.

Article en En | MEDLINE | ID: mdl-33085904

Asunto(s)

Antiinflamatorios/farmacología; Butiratos/farmacología; Colon/efectos de los fármacos; Enterocolitis Necrotizante/prevención & control; Enterocitos/efectos de los fármacos; Íleon/efectos de los fármacos; Mucosa Intestinal/efectos de los fármacos; Leche Humana/metabolismo; Animales; Animales Recién Nacidos; Butiratos/metabolismo; Línea Celular; Colon/metabolismo; Enterocolitis Necrotizante/metabolismo; Enterocitos/metabolismo; Femenino; Regulación de la Expresión Génica; Humanos; Íleon/metabolismo; Interleucina-1beta/farmacología; Mucosa Intestinal/metabolismo; Ratones Endogámicos C57BL; Moco/metabolismo; Permeabilidad; Uniones Estrechas/efectos de los fármacos; Uniones Estrechas/metabolismo; Técnicas de Cultivo de Tejidos; Transcriptoma

Palabras clave

butyrate; immature intestinal inflammation; mucus genes; tight junction genes

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Butiratos / Colon / Enterocolitis Necrotizante / Enterocitos / Íleon / Mucosa Intestinal / Antiinflamatorios / Leche Humana Límite: Animals / Female / Humans Idioma: En Revista: Am J Physiol Gastrointest Liver Physiol Asunto de la revista: FISIOLOGIA / GASTROENTEROLOGIA Año: 2021 Tipo del documento: Article

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