The Fuchs corneal dystrophy-associated CTG repeat expansion in the TCF4 gene affects transcription from its alternative promoters.

Sirp, Alex; Leite, Kristian; Tuvikene, Jürgen; Nurm, Kaja; Sepp, Mari; Timmusk, Tõnis

Sirp, Alex; Leite, Kristian; Tuvikene, Jürgen; Nurm, Kaja; Sepp, Mari; Timmusk, Tõnis.

Afiliación

Sirp A; Department of Chemistry and Biotechnology, Tallinn University of Technology, Akadeemia tee 15, 12618, Tallinn, Estonia.
Leite K; Department of Chemistry and Biotechnology, Tallinn University of Technology, Akadeemia tee 15, 12618, Tallinn, Estonia.
Tuvikene J; Department of Neurology, University Medicine Göttingen, Waldweg 33, 37073, Göttingen, Germany.
Nurm K; Department of Chemistry and Biotechnology, Tallinn University of Technology, Akadeemia tee 15, 12618, Tallinn, Estonia.
Sepp M; Protobios LLC, 12618, Tallinn, Estonia.
Timmusk T; Department of Chemistry and Biotechnology, Tallinn University of Technology, Akadeemia tee 15, 12618, Tallinn, Estonia.

Sci Rep ; 10(1): 18424, 2020 10 28.

Article en En | MEDLINE | ID: mdl-33116252

Asunto(s)

Distrofia Endotelial de Fuchs/genética; Factor de Transcripción 4/genética; Empalme Alternativo; Humanos; Regiones Promotoras Genéticas; Factor de Transcripción 4/metabolismo; Expansión de Repetición de Trinucleótido

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Distrofia Endotelial de Fuchs / Factor de Transcripción 4 Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Revista: Sci Rep Año: 2020 Tipo del documento: Article País de afiliación: Estonia

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