Non-Transcriptional and Translational Function of Canonical NF-<i>&#954;</i>B Signaling in Activating ERK1/2 in IL-1<i>ß</i>-Induced COX-2 Expression in Synovial Fibroblasts.

Nakano, Rei; Kitanaka, Taku; Namba, Shinichi; Kitanaka, Nanako; Suwabe, Yoko; Konno, Tadayoshi; Yamazaki, Jun; Nakayama, Tomohiro; Sugiya, Hiroshi

Non-Transcriptional and Translational Function of Canonical NF-κB Signaling in Activating ERK1/2 in IL-1ß-Induced COX-2 Expression in Synovial Fibroblasts.

Nakano, Rei; Kitanaka, Taku; Namba, Shinichi; Kitanaka, Nanako; Suwabe, Yoko; Konno, Tadayoshi; Yamazaki, Jun; Nakayama, Tomohiro; Sugiya, Hiroshi.

Afiliación

Nakano R; Laboratory for Cellular Function Conversion Technology, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
Kitanaka T; Laboratory of Veterinary Radiology, Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University, Fujisawa, Japan.
Namba S; Laboratory of Veterinary Biochemistry, Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University, Fujisawa, Japan.
Kitanaka N; Laboratory of Veterinary Radiology, Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University, Fujisawa, Japan.
Suwabe Y; Laboratory of Veterinary Biochemistry, Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University, Fujisawa, Japan.
Konno T; Laboratory of Veterinary Radiology, Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University, Fujisawa, Japan.
Yamazaki J; Laboratory of Veterinary Biochemistry, Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University, Fujisawa, Japan.
Nakayama T; Laboratory of Veterinary Radiology, Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University, Fujisawa, Japan.
Sugiya H; Laboratory of Veterinary Biochemistry, Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University, Fujisawa, Japan.

Front Immunol ; 11: 579266, 2020.

Article en En | MEDLINE | ID: mdl-33117381

Asunto(s)

Ciclooxigenasa 2/metabolismo; Fibroblastos/efectos de los fármacos; Interleucina-1beta/toxicidad; Proteína Quinasa 1 Activada por Mitógenos/metabolismo; Proteína Quinasa 3 Activada por Mitógenos/metabolismo; FN-kappa B/metabolismo; Membrana Sinovial/efectos de los fármacos; Sinovitis/inducido químicamente; Animales; Células Cultivadas; Ciclooxigenasa 2/genética; Perros; Activación Enzimática; Fibroblastos/enzimología; Fibroblastos/patología; FN-kappa B/genética; Fosforilación; Transducción de Señal; Membrana Sinovial/enzimología; Membrana Sinovial/patología; Sinovitis/enzimología; Sinovitis/patología

Palabras clave

ERK1/2; NF-κBnuclear factor kappa B; cyclooxygenase 2 (COX-2); interleukin 1ß (IL-1ß); rheumatoid arthritis

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Membrana Sinovial / Sinovitis / FN-kappa B / Proteína Quinasa 1 Activada por Mitógenos / Proteína Quinasa 3 Activada por Mitógenos / Ciclooxigenasa 2 / Interleucina-1beta / Fibroblastos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Front Immunol Año: 2020 Tipo del documento: Article País de afiliación: Japón

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google