A novel molecular magnetic resonance imaging agent targeting activated leukocyte cell adhesion molecule as demonstrated in mouse brain metastasis models.

Zarghami, Niloufar; Soto, Manuel Sarmiento; Perez-Balderas, Francisco; Khrapitchev, Alexandre A; Karali, Christina Simoglou; Johanssen, Vanessa A; Ansorge, Olaf; Larkin, James R; Sibson, Nicola R

Zarghami, Niloufar; Soto, Manuel Sarmiento; Perez-Balderas, Francisco; Khrapitchev, Alexandre A; Karali, Christina Simoglou; Johanssen, Vanessa A; Ansorge, Olaf; Larkin, James R; Sibson, Nicola R.

Afiliación

Zarghami N; Cancer Research UK and Medical Research Council Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, UK.
Soto MS; Cancer Research UK and Medical Research Council Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, UK.
Perez-Balderas F; Cancer Research UK and Medical Research Council Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, UK.
Khrapitchev AA; Cancer Research UK and Medical Research Council Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, UK.
Karali CS; Cancer Research UK and Medical Research Council Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, UK.
Johanssen VA; Cancer Research UK and Medical Research Council Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, UK.
Ansorge O; Department of Clinical Neuropathology, John Radcliffe Hospital, Oxford, UK.
Larkin JR; Cancer Research UK and Medical Research Council Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, UK.
Sibson NR; Cancer Research UK and Medical Research Council Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, UK.

J Cereb Blood Flow Metab ; 41(7): 1592-1607, 2021 07.

Article en En | MEDLINE | ID: mdl-33153376

Asunto(s)

Molécula de Adhesión Celular del Leucocito Activado/química; Adenocarcinoma del Pulmón/tratamiento farmacológico; Anticuerpos Monoclonales/farmacología; Neoplasias Encefálicas/tratamiento farmacológico; Neoplasias de la Mama/tratamiento farmacológico; Medios de Contraste/metabolismo; Melanoma/tratamiento farmacológico; Molécula de Adhesión Celular del Leucocito Activado/metabolismo; Adenocarcinoma del Pulmón/metabolismo; Adenocarcinoma del Pulmón/patología; Animales; Apoptosis; Neoplasias Encefálicas/metabolismo; Neoplasias Encefálicas/secundario; Neoplasias de la Mama/metabolismo; Neoplasias de la Mama/patología; Proliferación Celular; Femenino; Compuestos Férricos/química; Humanos; Neoplasias Pulmonares/tratamiento farmacológico; Neoplasias Pulmonares/metabolismo; Neoplasias Pulmonares/patología; Imagen por Resonancia Magnética; Melanoma/metabolismo; Melanoma/patología; Ratones; Ratones SCID; Invasividad Neoplásica; Células Tumorales Cultivadas; Ensayos Antitumor por Modelo de Xenoinjerto

Palabras clave

CD166); Magnetic resonance imaging; activated leukocyte cell adhesion molecule (ALCAM; brain metastasis; inflammation; molecular imaging

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias Encefálicas / Neoplasias de la Mama / Medios de Contraste / Molécula de Adhesión Celular del Leucocito Activado / Adenocarcinoma del Pulmón / Melanoma / Anticuerpos Monoclonales Límite: Animals / Female / Humans Idioma: En Revista: J Cereb Blood Flow Metab Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido

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