Levels of non-high-density-lipoprotein cholesterol are positively correlated with the risk of cognitive impairment in patients with intracerebral hemorrhage stroke.
Int J Neurosci
; 132(9): 910-916, 2022 Sep.
Article
en En
| MEDLINE
| ID: mdl-33175604
ABSTRACT
BACKGROUND:
Intracerebral hemorrhage (ICH) is one of the most common strokes, especially in developing countries. Recently, level of non-high-density lipoprotein cholesterol (non-HDL-C) has been implicated to be a better indicator for several lipid-related disorders. However, whether non-HDL-C can be used as an indicator for the risk of cognitive impairment in ICH patients remains to be elucidated.METHODS:
In this study, we performed a retrospective study on patients with ICH treated at our institution to investigate the association between the level of non-HDL-C and various neuropsychological assessments, including mini-mental state examination (MMSE), Montreal cognitive assessment (MoCA), activity of daily living scale (ADL), neuropsychiatric Inventory (NPI) and Hamilton depression rating scale 21 (HAMD21).RESULTS:
We found that all scores of the tested assessments were significantly altered in ICH patients with a high non-HDL-C level. In addition, we revealed that non-HDL-C was negatively correlated with MMSE and MoCA scores and was positively correlated with ADL, NPI and HAMD21 scores.CONCLUSIONS:
Our study suggests that non-HDL-C level can be used as a potential indicator for the risk of cognitive impairment in ICH patients.Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Accidente Cerebrovascular
/
Disfunción Cognitiva
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Accidente Cerebrovascular Hemorrágico
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Límite:
Humans
Idioma:
En
Revista:
Int J Neurosci
Año:
2022
Tipo del documento:
Article
País de afiliación:
China