Radiofrequency ablation versus surgical resection for the treatment of solitary hepatocellular carcinoma 2 cm or smaller: A cohort study in Taiwan.
J Formos Med Assoc
; 120(5): 1249-1258, 2021 May.
Article
en En
| MEDLINE
| ID: mdl-33288401
ABSTRACT
BACKGROUND/PURPOSE:
Radiofrequency ablation (RFA) is increasingly being used instead of surgical resection for the treatment of hepatocellular carcinoma (HCC) tumor measuring â¦2 cm. However, the long-term outcomes of RFA, especially in comparison to surgical resection, are still debated. We compared the outcomes of surgical resection and RFA in patients with a solitary HCC tumor measuring â¦2 cm from a 10-year cohort study.METHODS:
From Jan 2006 to Dec 2016, 156 patients with a resectable HCC measuring â¦2 cm who underwent surgical resection (n = 83) or RFA (n = 73) at the Buddhist Tzu Chi Medical Foundation were enrolled. Patient characteristics, overall survival (OS), and recurrence-free survival (RFS) were retrospectively examined, and comparisons were made between the two groups and through subgroup analyses.RESULTS:
The 1-year, 3-year, 5-year, and 7-year OS outcomes were comparable between the surgical resection group and the RFA group (P = 0.193), but the surgical resection group had significantly higher 1-year, 3-year, 5-year, 7-year, and 10-year RFS than the RFA group (P = 0.018). Multivariate analysis revealed that patients with lower age, Child-Turcotte-Pugh score, or albumin-bilirubin score before treatment had better OS, and patients with an HCV infection or receiving RFA treatment had higher HCC recurrence rates.CONCLUSION:
The liver reserve determined the long-term OS of patients with an HCC tumor ⦠2 cm, and surgical resection offered better RFS than RFA (ClinicalTrials.gov number, NCT04525833.).Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Ablación por Catéter
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Carcinoma Hepatocelular
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Ablación por Radiofrecuencia
/
Neoplasias Hepáticas
Tipo de estudio:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Risk_factors_studies
Límite:
Child
/
Humans
País/Región como asunto:
Asia
Idioma:
En
Revista:
J Formos Med Assoc
Asunto de la revista:
MEDICINA
Año:
2021
Tipo del documento:
Article