Selective Labeling and Identification of the Tumor Cell Proteome of Pancreatic Cancer <i>In Vivo</i>.

Azizian, Nancy G; Sullivan, Delaney K; Nie, Litong; Pardo, Sammy; Molleur, Dana; Chen, Junjie; Weintraub, Susan T; Li, Yulin

Selective Labeling and Identification of the Tumor Cell Proteome of Pancreatic Cancer In Vivo.

Azizian, Nancy G; Sullivan, Delaney K; Nie, Litong; Pardo, Sammy; Molleur, Dana; Chen, Junjie; Weintraub, Susan T; Li, Yulin.

Afiliación

Azizian NG; Center for Immunotherapy Research, Houston Methodist Research Institute, Houston, Texas 77030, United States.
Sullivan DK; Department of Medicine, Weill Cornell Medical College, New York, New York 10065, United States.
Nie L; UCLA-Caltech Medical Scientist Training Program, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California 90095, United States.
Pardo S; Department of Experimental Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, United States.
Molleur D; Department of Biochemistry and Structural Biology, The University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229, United States.
Chen J; Department of Biochemistry and Structural Biology, The University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229, United States.
Weintraub ST; Department of Experimental Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, United States.
Li Y; Department of Biochemistry and Structural Biology, The University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229, United States.

J Proteome Res ; 20(1): 858-866, 2021 01 01.

Article en En | MEDLINE | ID: mdl-33289385

Asunto(s)

Aminoacil-ARNt Sintetasas; Carcinoma Ductal Pancreático; Neoplasias Pancreáticas; Aminoácidos; Azidas; Carcinoma Ductal Pancreático/genética; Humanos; Neoplasias Pancreáticas/genética; Proteoma/genética; Microambiente Tumoral

Palabras clave

azidonorleucine (ANL); bioorthogonal noncanonical amino acid tagging (BONCAT); data-independent acquisition mass spectrometry (DIA-MS); methionyl-tRNA synthetase (MetRS); pancreatic ductal adenocarcinoma (PDAC); patient-derived xenografts (PDX)

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Carcinoma Ductal Pancreático / Aminoacil-ARNt Sintetasas Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: J Proteome Res Asunto de la revista: BIOQUIMICA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos

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