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A Small Molecule Inhibitor of VE-PTP Activates Tie2 in Schlemm's Canal Increasing Outflow Facility and Reducing Intraocular Pressure.
Li, Guorong; Nottebaum, Astrid F; Brigell, Mitchell; Navarro, Iris D; Ipe, Ute; Mishra, Sarthak; Gomez-Caraballo, Maria; Schmitt, Heather; Soldo, Brandi; Pakola, Steve; Withers, Barbara; Peters, Kevin G; Vestweber, Dietmar; Stamer, W Daniel.
Afiliación
  • Li G; Department of Ophthalmology, Department of Biomedical Engineering, Duke University, Durham, North Carolina, United States.
  • Nottebaum AF; Max Planck Institute of Molecular Biomedicine, Muenster, Germany.
  • Brigell M; Aerpio Pharmaceuticals, Inc., Cincinnati, Ohio, United States.
  • Navarro ID; Department of Ophthalmology, Department of Biomedical Engineering, Duke University, Durham, North Carolina, United States.
  • Ipe U; Max Planck Institute of Molecular Biomedicine, Muenster, Germany.
  • Mishra S; Max Planck Institute of Molecular Biomedicine, Muenster, Germany.
  • Gomez-Caraballo M; Department of Ophthalmology, Department of Biomedical Engineering, Duke University, Durham, North Carolina, United States.
  • Schmitt H; Department of Ophthalmology, Department of Biomedical Engineering, Duke University, Durham, North Carolina, United States.
  • Soldo B; Aerpio Pharmaceuticals, Inc., Cincinnati, Ohio, United States.
  • Pakola S; Aerpio Pharmaceuticals, Inc., Cincinnati, Ohio, United States.
  • Withers B; Aerpio Pharmaceuticals, Inc., Cincinnati, Ohio, United States.
  • Peters KG; Aerpio Pharmaceuticals, Inc., Cincinnati, Ohio, United States.
  • Vestweber D; Max Planck Institute of Molecular Biomedicine, Muenster, Germany.
  • Stamer WD; Department of Ophthalmology, Department of Biomedical Engineering, Duke University, Durham, North Carolina, United States.
Invest Ophthalmol Vis Sci ; 61(14): 12, 2020 12 01.
Article en En | MEDLINE | ID: mdl-33315051
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Ácidos Sulfónicos / Malla Trabecular / Receptor TIE-2 / Proteínas Tirosina Fosfatasas Clase 3 Similares a Receptores / Presión Intraocular / Compuestos de Anilina Tipo de estudio: Clinical_trials Límite: Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Invest Ophthalmol Vis Sci Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Ácidos Sulfónicos / Malla Trabecular / Receptor TIE-2 / Proteínas Tirosina Fosfatasas Clase 3 Similares a Receptores / Presión Intraocular / Compuestos de Anilina Tipo de estudio: Clinical_trials Límite: Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Invest Ophthalmol Vis Sci Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos