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Dissecting strategies to tune the therapeutic potential of SARS-CoV-2-specific monoclonal antibody CR3022.
Atyeo, Caroline; Slein, Matthew D; Fischinger, Stephanie; Burke, John; Schäfer, Alexandra; Leist, Sarah R; Kuzmina, Natalia A; Mire, Chad; Honko, Anna; Johnson, Rebecca; Storm, Nadia; Bernett, Matthew; Tong, Pei; Zuo, Teng; Lin, Junrui; Zuiani, Adam; Linde, Caitlyn; Suscovich, Todd; Wesemann, Duane R; Griffiths, Anthony; Desjarlais, John R; Juelg, Boris D; Goudsmit, Jaap; Bukreyev, Alexander; Baric, Ralph; Alter, Galit.
Afiliación
  • Atyeo C; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, USA.
  • Slein MD; Program in Virology, Division of Medical Sciences, Harvard University, Boston, Massachusetts, USA.
  • Fischinger S; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, USA.
  • Burke J; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, USA.
  • Schäfer A; Program in Immunology and Virology, University of Duisburg-Essen, Essen, Germany.
  • Leist SR; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, USA.
  • Kuzmina NA; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
  • Mire C; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
  • Honko A; Department of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.
  • Johnson R; Galveston National Laboratory, Institute for Human Infections and Immunity, University of Texas Medical Branch, Galveston, Texas, USA.
  • Storm N; Department of Pathology, University of Texas Medical Branch, Galveston, Texas, USA.
  • Bernett M; Galveston National Laboratory, Institute for Human Infections and Immunity, University of Texas Medical Branch, Galveston, Texas, USA.
  • Tong P; Department of Microbiology, Boston University School of Medicine, Boston, Massachusetts, USA.
  • Zuo T; National Emerging Infectious Diseases Laboratories, Boston University, Boston, Massachusetts, USA.
  • Lin J; Department of Microbiology, Boston University School of Medicine, Boston, Massachusetts, USA.
  • Zuiani A; National Emerging Infectious Diseases Laboratories, Boston University, Boston, Massachusetts, USA.
  • Linde C; Department of Microbiology, Boston University School of Medicine, Boston, Massachusetts, USA.
  • Suscovich T; National Emerging Infectious Diseases Laboratories, Boston University, Boston, Massachusetts, USA.
  • Wesemann DR; Xencor, Monrovia, California, USA.
  • Griffiths A; Department of Medicine, Brigham and Women's Hospital; Division of Allergy and Clinical Immunology; and Division of Genetics, Harvard Medical School, Boston, Massachusetts, USA.
  • Desjarlais JR; Department of Medicine, Brigham and Women's Hospital; Division of Allergy and Clinical Immunology; and Division of Genetics, Harvard Medical School, Boston, Massachusetts, USA.
  • Juelg BD; Department of Medicine, Brigham and Women's Hospital; Division of Allergy and Clinical Immunology; and Division of Genetics, Harvard Medical School, Boston, Massachusetts, USA.
  • Goudsmit J; Department of Medicine, Brigham and Women's Hospital; Division of Allergy and Clinical Immunology; and Division of Genetics, Harvard Medical School, Boston, Massachusetts, USA.
  • Bukreyev A; SeromYx Systems, Cambridge, Massachusetts, USA.
  • Baric R; SeromYx Systems, Cambridge, Massachusetts, USA.
  • Alter G; Department of Medicine, Brigham and Women's Hospital; Division of Allergy and Clinical Immunology; and Division of Genetics, Harvard Medical School, Boston, Massachusetts, USA.
JCI Insight ; 6(1)2021 01 11.
Article en En | MEDLINE | ID: mdl-33427208
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Replicación Viral / Inmunoglobulina G / Fragmentos Fc de Inmunoglobulinas / Anticuerpos Neutralizantes / SARS-CoV-2 / COVID-19 / Inmunidad Innata Límite: Animals / Humans Idioma: En Revista: JCI Insight Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Replicación Viral / Inmunoglobulina G / Fragmentos Fc de Inmunoglobulinas / Anticuerpos Neutralizantes / SARS-CoV-2 / COVID-19 / Inmunidad Innata Límite: Animals / Humans Idioma: En Revista: JCI Insight Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos