Acute perturbation strategies in interrogating RNA polymerase II elongation factor function in gene expression.

Zheng, Bin; Aoi, Yuki; Shah, Avani P; Iwanaszko, Marta; Das, Siddhartha; Rendleman, Emily J; Zha, Didi; Khan, Nabiha; Smith, Edwin R; Shilatifard, Ali

Zheng, Bin; Aoi, Yuki; Shah, Avani P; Iwanaszko, Marta; Das, Siddhartha; Rendleman, Emily J; Zha, Didi; Khan, Nabiha; Smith, Edwin R; Shilatifard, Ali.

Afiliación

Zheng B; Simpson Querrey Institute for Epigenetics, Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA.
Aoi Y; Simpson Querrey Institute for Epigenetics, Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA.
Shah AP; Simpson Querrey Institute for Epigenetics, Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA.
Iwanaszko M; Simpson Querrey Institute for Epigenetics, Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA.
Das S; Simpson Querrey Institute for Epigenetics, Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA.
Rendleman EJ; Simpson Querrey Institute for Epigenetics, Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA.
Zha D; Simpson Querrey Institute for Epigenetics, Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA.
Khan N; Simpson Querrey Institute for Epigenetics, Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA.
Smith ER; Simpson Querrey Institute for Epigenetics, Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA.
Shilatifard A; Simpson Querrey Institute for Epigenetics, Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA.

Genes Dev ; 35(3-4): 273-285, 2021 02 01.

Article en En | MEDLINE | ID: mdl-33446572

Asunto(s)

Expresión Génica/genética; Factores de Elongación de Péptidos/metabolismo; ARN Polimerasa II/metabolismo; Factores de Transcripción/metabolismo; Proteínas de Ciclo Celular/genética; Proteínas de Ciclo Celular/metabolismo; Línea Celular Tumoral; Células HCT116; Respuesta al Choque Térmico; Humanos; Factores de Elongación de Péptidos/genética; Proteínas/genética; Proteínas/metabolismo; ARN Polimerasa II/genética; Factores de Transcripción/genética

Palabras clave

BRD2; BRD4; PROTAC; auxin-inducible degradation; enhancer activity; heat shock; super elongation complex; transcription elongation

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Factores de Transcripción / ARN Polimerasa II / Expresión Génica / Factores de Elongación de Péptidos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Genes Dev Asunto de la revista: BIOLOGIA MOLECULAR Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos

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