Combined exenatide and dapagliflozin has no additive effects on reduction of hepatocellular lipids despite better glycaemic control in patients with type 2 diabetes mellitus treated with metformin: EXENDA, a 24-week, prospective, randomized, placebo-controlled pilot trial.

Harreiter, Jürgen; Just, Ivica; Leutner, Michael; Bastian, Magdalena; Brath, Helmut; Schelkshorn, Christian; Klepochova, Radka; Krssák, Martin; Kautzky-Willer, Alexandra

Harreiter, Jürgen; Just, Ivica; Leutner, Michael; Bastian, Magdalena; Brath, Helmut; Schelkshorn, Christian; Klepochova, Radka; Krssák, Martin; Kautzky-Willer, Alexandra.

Afiliación

Harreiter J; Gender Medicine Unit, Division of Endocrinology and Metabolism, Department of Medicine III, Medical University Vienna, Vienna, Austria.
Just I; Department of Biomedical Imaging and Image-Guided Therapy, High-Field MR Center, Medical University of Vienna, Vienna, Austria.
Leutner M; Division of Endocrinology and Metabolism, Department of Medicine III, Medical University Vienna, Vienna, Austria.
Bastian M; Gender Medicine Unit, Division of Endocrinology and Metabolism, Department of Medicine III, Medical University Vienna, Vienna, Austria.
Brath H; Gender Medicine Unit, Division of Endocrinology and Metabolism, Department of Medicine III, Medical University Vienna, Vienna, Austria.
Schelkshorn C; Diabetes Outpatient Clinic, Health Centre Favoriten, Vienna, Austria.
Klepochova R; Department of Medicine, State Hospital Stockerau, Stockerau, Austria.
Krssák M; Department of Biomedical Imaging and Image-Guided Therapy, High-Field MR Center, Medical University of Vienna, Vienna, Austria.
Kautzky-Willer A; Division of Endocrinology and Metabolism, Department of Medicine III, Medical University Vienna, Vienna, Austria.

Diabetes Obes Metab ; 23(5): 1129-1139, 2021 05.

Article en En | MEDLINE | ID: mdl-33464703

Asunto(s)

Carcinoma Hepatocelular; Diabetes Mellitus Tipo 2; Neoplasias Hepáticas; Metformina; Adolescente; Adulto; Anciano; Compuestos de Bencidrilo; Glucemia; Diabetes Mellitus Tipo 2/tratamiento farmacológico; Método Doble Ciego; Quimioterapia Combinada; Exenatida/uso terapéutico; Glucósidos; Hemoglobina Glucada; Control Glucémico; Humanos; Hipoglucemiantes/uso terapéutico; Lípidos; Metformina/uso terapéutico; Persona de Mediana Edad; Proyectos Piloto; Estudios Prospectivos; Resultado del Tratamiento; Adulto Joven

Palabras clave

CVD; GLP-1 receptor agonist; NAFLD; SGLT2 inhibitor; ectopic lipids; glycaemic control; magnetic resonance imaging; metabolic syndrome; obesity; prevention; type 2 diabetes mellitus; weight loss

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Carcinoma Hepatocelular / Diabetes Mellitus Tipo 2 / Neoplasias Hepáticas / Metformina Tipo de estudio: Clinical_trials / Observational_studies / Prognostic_studies Límite: Adolescent / Adult / Aged / Humans / Middle aged Idioma: En Revista: Diabetes Obes Metab Asunto de la revista: ENDOCRINOLOGIA / METABOLISMO Año: 2021 Tipo del documento: Article País de afiliación: Austria

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