Quantitative peripheral computed tomography to measure muscle area and assess lean soft tissue mass in children.
Ann Hum Biol
; 48(2): 93-100, 2021 Mar.
Article
en En
| MEDLINE
| ID: mdl-33470135
ABSTRACT
BACKGROUND:
Skeletal muscle is one of the main components of lean soft tissue mass (LSTM). Low levels in children affect locomotion, posture, and increase the risk of metabolic syndrome.AIM:
(1) To evaluate the association between muscle cross-sectional area (MCSA) of the lower left leg measured by peripheral quantitative computed tomography (pQCT) and total LSTM; namely, total left leg and left lower leg LSTM assessed by dual-energy X-ray absorptiometry (DXA) in a group of children, (2) to examine if MCSA is a predictor of LSTM, (3) to determine the ability of pQCT to identify children with low LSTM. SUBJECTS ANDMETHODS:
Lower left leg MCSA and LSTM were measured using pQCT and DXA, respectively, in 396 children.RESULTS:
Statistically significant positive correlations were found between the lower leg MCSA - total LSTM (r² = 0.789), total leg LSTM (r² = 0.79), and lower leg LSTM (r² = 0.791) (p < .01). MCSA explained 64-68% of the variance in LSTM. Receiver operator characteristic (ROC) curves determined the capacity of the lower left leg MCSA to identify low LSTM in girls (AUC 0.95) and boys (AUC 0.87).CONCLUSIONS:
Our results showed that lower left leg MCSA, measured using pQCT, could be a tool to predict low LSTM in children.Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Tomografía Computarizada por Rayos X
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Absorciometría de Fotón
/
Músculo Esquelético
/
Pierna
Tipo de estudio:
Prognostic_studies
Límite:
Child
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Female
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Humans
/
Male
Idioma:
En
Revista:
Ann Hum Biol
Año:
2021
Tipo del documento:
Article
País de afiliación:
Colombia