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Small-molecule screen reveals synergy of cell cycle checkpoint kinase inhibitors with DNA-damaging chemotherapies in medulloblastoma.
Endersby, Raelene; Whitehouse, Jacqueline; Pribnow, Allison; Kuchibhotla, Mani; Hii, Hilary; Carline, Brooke; Gande, Suresh; Stripay, Jennifer; Ancliffe, Mathew; Howlett, Meegan; Schoep, Tobias; George, Courtney; Andradas, Clara; Dyer, Patrick; Schluck, Marjolein; Patterson, Brett; Tacheva-Gigorova, Silvia K; Cooper, Matthew N; Robinson, Giles; Stewart, Clinton; Pfister, Stefan M; Kool, Marcel; Milde, Till; Gajjar, Amar; Johns, Terrance; Wechsler-Reya, Robert J; Roussel, Martine F; Gottardo, Nicholas G.
Afiliación
  • Endersby R; Brain Tumour Research Program, Telethon Kids Institute, Nedlands, WA 6009, Australia. raelene.endersby@telethonkids.org.au nick.gottardo@health.wa.edu.au.
  • Whitehouse J; Division of Paediatrics/Centre for Child Health Research, Medical School, University of Western Australia, Crawley, WA 6009, Australia.
  • Pribnow A; Brain Tumour Research Program, Telethon Kids Institute, Nedlands, WA 6009, Australia.
  • Kuchibhotla M; Division of Paediatrics/Centre for Child Health Research, Medical School, University of Western Australia, Crawley, WA 6009, Australia.
  • Hii H; Division of Hematology/Oncology, Department of Pediatrics, Stanford University School of Medicine, Palo Alto, CA 94305, USA.
  • Carline B; Brain Tumour Research Program, Telethon Kids Institute, Nedlands, WA 6009, Australia.
  • Gande S; Brain Tumour Research Program, Telethon Kids Institute, Nedlands, WA 6009, Australia.
  • Stripay J; Brain Tumour Research Program, Telethon Kids Institute, Nedlands, WA 6009, Australia.
  • Ancliffe M; Brain Tumour Research Program, Telethon Kids Institute, Nedlands, WA 6009, Australia.
  • Howlett M; Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, TN 38103, USA.
  • Schoep T; Brain Tumour Research Program, Telethon Kids Institute, Nedlands, WA 6009, Australia.
  • George C; Brain Tumour Research Program, Telethon Kids Institute, Nedlands, WA 6009, Australia.
  • Andradas C; Division of Paediatrics/Centre for Child Health Research, Medical School, University of Western Australia, Crawley, WA 6009, Australia.
  • Dyer P; Brain Tumour Research Program, Telethon Kids Institute, Nedlands, WA 6009, Australia.
  • Schluck M; Brain Tumour Research Program, Telethon Kids Institute, Nedlands, WA 6009, Australia.
  • Patterson B; Brain Tumour Research Program, Telethon Kids Institute, Nedlands, WA 6009, Australia.
  • Tacheva-Gigorova SK; Division of Paediatrics/Centre for Child Health Research, Medical School, University of Western Australia, Crawley, WA 6009, Australia.
  • Cooper MN; Brain Tumour Research Program, Telethon Kids Institute, Nedlands, WA 6009, Australia.
  • Robinson G; Division of Paediatrics/Centre for Child Health Research, Medical School, University of Western Australia, Crawley, WA 6009, Australia.
  • Stewart C; Brain Tumour Research Program, Telethon Kids Institute, Nedlands, WA 6009, Australia.
  • Pfister SM; Department of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen 6525 GA, Netherlands.
  • Kool M; Brain Tumour Research Program, Telethon Kids Institute, Nedlands, WA 6009, Australia.
  • Milde T; Tumor Initiation and Maintenance Program, NCI-Designated Cancer Center, Sanford-Burnham-Prebys Medical Discovery Institute, La Jolla, CA 92037, USA.
  • Gajjar A; Biometrics, Telethon Kids Institute, University of Western Australia, Nedlands, WA 6009, Australia.
  • Johns T; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN 38103, USA.
  • Wechsler-Reya RJ; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN 38103, USA.
  • Roussel MF; Hopp Children's Cancer Center (KiTZ) and German Cancer Research Center (DKFZ), Heidelberg 69120, Germany.
  • Gottardo NG; Department of Pediatric Hematology and Oncology, Heidelberg University Hospital, Heidelberg 69120, Germany.
Sci Transl Med ; 13(577)2021 01 20.
Article en En | MEDLINE | ID: mdl-33472956
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias Cerebelosas / Meduloblastoma Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2021 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias Cerebelosas / Meduloblastoma Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2021 Tipo del documento: Article