Malignant Degeneration of Biopsy-Proven Hamartoma to Chondrosarcoma.
Cureus
; 12(12): e12150, 2020 Dec 18.
Article
en En
| MEDLINE
| ID: mdl-33489562
ABSTRACT
Pulmonary hamartomas are benign lesions that are often managed conservatively in the absence of respiratory symptoms. Increasing reports of malignant transformation question if a more aggressive treatment or surveillance practice for these lesions is warranted in adult patients. Herein, we describe a case of a 67-year-old man with a long history of pulmonary hamartoma that demonstrated malignant degeneration into spindle cell malignancy with chondromatous differentiation. This case illustrates the aggressive nature of sarcomatous disease arising from hamartomas and, with a handful of other cases in the literature, points to the question of whether pulmonary hamartomas arising in late adulthood should follow a more intensive treatment or surveillance algorithm given increased concern for malignant potential.
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Bases de datos:
MEDLINE
Idioma:
En
Revista:
Cureus
Año:
2020
Tipo del documento:
Article
País de afiliación:
Estados Unidos