SMAD-specific E3 ubiquitin ligase 2 promotes angiogenesis by facilitating PTX3 degradation in MSCs from patients with ankylosing spondylitis.

Ma, Mengjun; Yang, Wen; Cai, Zhaopeng; Wang, Peng; Li, Hongyu; Mi, Rujia; Jiang, Yuhang; Xie, Zhongyu; Sui, Pengfei; Wu, Yanfeng; Shen, Huiyong

Ma, Mengjun; Yang, Wen; Cai, Zhaopeng; Wang, Peng; Li, Hongyu; Mi, Rujia; Jiang, Yuhang; Xie, Zhongyu; Sui, Pengfei; Wu, Yanfeng; Shen, Huiyong.

Afiliación

Ma M; Department of Orthopedics, The Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen, Guangdong, People's Republic of China.
Yang W; Department of Orthopedics, The Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen, Guangdong, People's Republic of China.
Cai Z; Department of Orthopedics, The Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen, Guangdong, People's Republic of China.
Wang P; Department of Orthopedics, The Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen, Guangdong, People's Republic of China.
Li H; Department of Orthopedics, The Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen, Guangdong, People's Republic of China.
Mi R; Center for Biotherapy, The Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen, Guangdong, People's Republic of China.
Jiang Y; Department of Orthopedics, The Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen, Guangdong, People's Republic of China.
Xie Z; Department of Orthopedics, The Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen, Guangdong, People's Republic of China.
Sui P; State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, People's Republic of China.
Wu Y; Center for Biotherapy, The Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen, Guangdong, People's Republic of China.
Shen H; Department of Orthopedics, The Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen, Guangdong, People's Republic of China.

Stem Cells ; 39(5): 581-599, 2021 05.

Article en En | MEDLINE | ID: mdl-33547700

Asunto(s)

Proteína C-Reactiva/genética; Neovascularización Patológica/genética; Componente Amiloide P Sérico/genética; Espondilitis Anquilosante/genética; Ubiquitina-Proteína Ligasas/genética; Factor de Transcripción Activador 4/genética; Movimiento Celular/genética; Técnicas de Cocultivo; Estrés del Retículo Endoplásmico/genética; Factor 2 de Crecimiento de Fibroblastos/genética; Regulación del Desarrollo de la Expresión Génica/genética; Voluntarios Sanos; Células Endoteliales de la Vena Umbilical Humana; Humanos; Células Madre Mesenquimatosas/metabolismo; Neovascularización Patológica/complicaciones; Neovascularización Patológica/patología; Espondilitis Anquilosante/complicaciones; Espondilitis Anquilosante/patología; Ubiquitina-Proteína Ligasas/antagonistas & inhibidores

Palabras clave

angiogenesis; arthritis; autoimmune disease; mesenchymal stem cells (MSCs); tube formation

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Espondilitis Anquilosante / Proteína C-Reactiva / Componente Amiloide P Sérico / Ubiquitina-Proteína Ligasas / Neovascularización Patológica Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Stem Cells Año: 2021 Tipo del documento: Article

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