Enisamium Reduces Influenza Virus Shedding and Improves Patient Recovery by Inhibiting Viral RNA Polymerase Activity.

Te Velthuis, Aartjan J W; Zubkova, Tatiana G; Shaw, Megan; Mehle, Andrew; Boltz, David; Gmeinwieser, Norbert; Stammer, Holger; Milde, Jens; Müller, Lutz; Margitich, Victor

Te Velthuis, Aartjan J W; Zubkova, Tatiana G; Shaw, Megan; Mehle, Andrew; Boltz, David; Gmeinwieser, Norbert; Stammer, Holger; Milde, Jens; Müller, Lutz; Margitich, Victor.

Afiliación

Te Velthuis AJW; Division of Virology, Department of Pathology, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom aj.te.velthuis@princeton.edu lutz.mueller@regenold.com.
Zubkova TG; Smorodintsev Research Institute of Influenza, Ministry of Health of the Russian Federation, Saint Petersburg, Russia.
Shaw M; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Mehle A; Department of Medical Microbiology & Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Boltz D; IIT Research Institute, Chicago, Illinois, USA.
Gmeinwieser N; Pharmalog Institut für klinische Forschung GmbH, Ismaning, Germany.
Stammer H; Pharmalog Institut für klinische Forschung GmbH, Ismaning, Germany.
Milde J; Pharmalog Institut für klinische Forschung GmbH, Ismaning, Germany.
Müller L; Dr. Regenold GmbH, Badenweiler, Germany aj.te.velthuis@princeton.edu lutz.mueller@regenold.com.
Margitich V; Farmak JSC, Kyiv, Ukraine.

Antimicrob Agents Chemother ; 65(4)2021 03 18.

Article en En | MEDLINE | ID: mdl-33558285

Asunto(s)

Gripe Humana; Orthomyxoviridae; Infecciones del Sistema Respiratorio; Adolescente; Adulto; Humanos; Gripe Humana/tratamiento farmacológico; Persona de Mediana Edad; Compuestos de Piridinio; ARN Viral; Infecciones del Sistema Respiratorio/tratamiento farmacológico; Proteinas del Complejo de Replicasa Viral; Esparcimiento de Virus; Adulto Joven

Palabras clave

FAV00A; RNA polymerase; RNA synthesis; adenovirus; adenoviruses; enisamium iodide; influenza A and B; influenza A and B viruses; respiratory syncytial virus; respiratory viruses; treatment

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Orthomyxoviridae / Infecciones del Sistema Respiratorio / Gripe Humana Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Adolescent / Adult / Humans / Middle aged Idioma: En Revista: Antimicrob Agents Chemother Año: 2021 Tipo del documento: Article

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