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Biallelic loss of BCMA as a resistance mechanism to CAR T cell therapy in a patient with multiple myeloma.
Samur, Mehmet Kemal; Fulciniti, Mariateresa; Aktas Samur, Anil; Bazarbachi, Abdul Hamid; Tai, Yu-Tzu; Prabhala, Rao; Alonso, Alejandro; Sperling, Adam S; Campbell, Timothy; Petrocca, Fabio; Hege, Kristen; Kaiser, Shari; Loiseau, Hervé Avet; Anderson, Kenneth C; Munshi, Nikhil C.
Afiliación
  • Samur MK; Department of Data Science, Dana Farber Cancer Institute, Boston, MA, USA. mehmet_samur@dfci.harvard.edu.
  • Fulciniti M; Department of Biostatistics, Harvard T. H. Chan School of Public Health Boston, Boston, MA, USA. mehmet_samur@dfci.harvard.edu.
  • Aktas Samur A; Department of Medical Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA. mehmet_samur@dfci.harvard.edu.
  • Bazarbachi AH; Department of Medical Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Tai YT; Department of Data Science, Dana Farber Cancer Institute, Boston, MA, USA.
  • Prabhala R; Department of Biostatistics, Harvard T. H. Chan School of Public Health Boston, Boston, MA, USA.
  • Alonso A; Department of Medical Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Sperling AS; Department of Internal Medicine, Jacobi Medical Center, Albert Einstein College of Medicine, New York, NY, USA.
  • Campbell T; Department of Medical Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Petrocca F; Department of Medical Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Hege K; VA Boston Healthcare System, Boston, MA, USA.
  • Kaiser S; Department of Medical Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Loiseau HA; Department of Medical Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Anderson KC; Bristol-Myers Squibb, San Francisco, CA, USA.
  • Munshi NC; Bluebird Bio, Cambridge, MA, USA.
Nat Commun ; 12(1): 868, 2021 02 08.
Article en En | MEDLINE | ID: mdl-33558511
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Inmunoterapia Adoptiva / Resistencia a Antineoplásicos / Alelos / Antígeno de Maduración de Linfocitos B / Mieloma Múltiple Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Inmunoterapia Adoptiva / Resistencia a Antineoplásicos / Alelos / Antígeno de Maduración de Linfocitos B / Mieloma Múltiple Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos