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Assessment of the impact of mitochondrial genotype upon drug-induced mitochondrial dysfunction in platelets derived from healthy volunteers.
Ball, Amy L; Bloch, Katarzyna M; Rainbow, Lucille; Liu, Xuan; Kenny, John; Lyon, Jonathan J; Gregory, Richard; Alfirevic, Ana; Chadwick, Amy E.
Afiliación
  • Ball AL; Department of Pharmacology and Therapeutics, MRC Centre for Drug Safety Science, University of Liverpool, Liverpool, UK.
  • Bloch KM; The Wolfson Centre for Personalised Medicine, Department of Pharmacology and Therapeutics, University of Liverpool, Liverpool, UK.
  • Rainbow L; Centre for Genomic Research, Institute of Integrative Biology, University of Liverpool, Liverpool, UK.
  • Liu X; Centre for Genomic Research, Institute of Integrative Biology, University of Liverpool, Liverpool, UK.
  • Kenny J; Centre for Genomic Research, Institute of Integrative Biology, University of Liverpool, Liverpool, UK.
  • Lyon JJ; GSK GlaxoSmithKline, Safety Assessment, Ware, UK.
  • Gregory R; Centre for Genomic Research, Institute of Integrative Biology, University of Liverpool, Liverpool, UK.
  • Alfirevic A; The Wolfson Centre for Personalised Medicine, Department of Pharmacology and Therapeutics, University of Liverpool, Liverpool, UK.
  • Chadwick AE; Department of Pharmacology and Therapeutics, MRC Centre for Drug Safety Science, University of Liverpool, Liverpool, UK. Amy.Chadwick@liverpool.ac.uk.
Arch Toxicol ; 95(4): 1335-1347, 2021 04.
Article en En | MEDLINE | ID: mdl-33585966

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Plaquetas / ADN Mitocondrial / Flutamida / Tolcapona Tipo de estudio: Prognostic_studies Límite: Adolescent / Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Arch Toxicol Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Plaquetas / ADN Mitocondrial / Flutamida / Tolcapona Tipo de estudio: Prognostic_studies Límite: Adolescent / Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Arch Toxicol Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido