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Population-specific causal disease effect sizes in functionally important regions impacted by selection.
Shi, Huwenbo; Gazal, Steven; Kanai, Masahiro; Koch, Evan M; Schoech, Armin P; Siewert, Katherine M; Kim, Samuel S; Luo, Yang; Amariuta, Tiffany; Huang, Hailiang; Okada, Yukinori; Raychaudhuri, Soumya; Sunyaev, Shamil R; Price, Alkes L.
Afiliación
  • Shi H; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA. hshi@hsph.harvard.edu.
  • Gazal S; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA. hshi@hsph.harvard.edu.
  • Kanai M; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
  • Koch EM; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Schoech AP; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Siewert KM; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.
  • Kim SS; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Luo Y; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
  • Amariuta T; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.
  • Huang H; Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Okada Y; Department of Medicine, Harvard Medical School, Boston, MA, USA.
  • Raychaudhuri S; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
  • Sunyaev SR; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Price AL; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Nat Commun ; 12(1): 1098, 2021 02 17.
Article en En | MEDLINE | ID: mdl-33597505
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Selección Genética / Desequilibrio de Ligamiento / Polimorfismo de Nucleótido Simple / Estudio de Asociación del Genoma Completo / Genética de Población Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Selección Genética / Desequilibrio de Ligamiento / Polimorfismo de Nucleótido Simple / Estudio de Asociación del Genoma Completo / Genética de Población Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos