Diagnostic accuracy of Quantitative Colour Doppler Flow imaging in distinguishing Persistent Fetal Vasculature from Retinal Detachment.
Acta Ophthalmol
; 100(2): 196-202, 2022 Mar.
Article
en En
| MEDLINE
| ID: mdl-33629492
ABSTRACT
PURPOSE:
Distinguishing posterior persistent fetal vasculature (PFV) from retinal detachment (RD) may be very challenging clinically and ultrasonographically, as they share common morphological features. However, it is crucial, considering their substantially distinct management and treatment. We aimed to assess the relevance of quantitative colour Doppler flow imaging to distinguish PFV from RD in children.METHODS:
This retrospective bi-centre study included 66 children (30 females and 36 males, mean age 244 ± 257 days) with a clinically suspected diagnosis of RD or posterior PFV. All children underwent systematic and standardized conventional ultrasonography and colour Doppler flow imaging under general anaesthesia with a qualitative and quantitative analysis of the retrolental tissue's vascularization. Peak systolic velocity, end-diastolic velocity and resistive index were recorded for analysis. Whenever available, surgical findings were deemed gold standard for diagnosis. A Mann-Whitney U-test was used to compare quantitative colour Doppler flow imaging data.RESULTS:
Peak systolic velocity and end-diastolic velocity were significantly lower in children with PFV versus RD 2.7 (IQR 0.5) versus 5.1 (IQR 2.8), p < 0.001, and 0.0 (IQR 0.0) versus 2.0 (IQR 1.2), p < 0.001, respectively. Resistive index was significantly higher in children with PFV versus RD 1 (IQR 0) versus 0.6 (IQR 0.1), p < 0.001. Area under curves (AUCs) were of 0.94, 0.99 and 1, respectively. No differences between PFV and RD were observed on structural ultrasound or qualitative analysis of colour Doppler.CONCLUSION:
Quantitative colour Doppler flow imaging has an excellent accuracy in distinguishing PFV from RD in children. It may help to improve management and treatment.Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Desprendimiento de Retina
/
Ultrasonografía Doppler en Color
/
Vítreo Primario Hiperplásico Persistente
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
/
Qualitative_research
Límite:
Female
/
Humans
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Infant
/
Male
Idioma:
En
Revista:
Acta Ophthalmol
Asunto de la revista:
OFTALMOLOGIA
Año:
2022
Tipo del documento:
Article
País de afiliación:
Francia