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Chronic phenmetrazine treatment promotes D2 dopaminergic and α2-adrenergic receptor desensitization and alters phosphorylation of signaling proteins and local cerebral glucose metabolism in the rat brain.
Keegan, Bradley M; Dreitzler, Annie L; Sexton, Tammy; Beveridge, Thomas J R; Smith, Hilary R; Miller, Mack D; Blough, Bruce E; Porrino, Linda J; Childers, Steven R; Howlett, Allyn C.
Afiliación
  • Keegan BM; Center for the Neurobiology of Addiction Treatment, Department of Physiology and Pharmacology, Wake Forest School of Medicine, Medical Center Blvd., Winston-Salem, NC 27157, USA.
  • Dreitzler AL; Center for the Neurobiology of Addiction Treatment, Department of Physiology and Pharmacology, Wake Forest School of Medicine, Medical Center Blvd., Winston-Salem, NC 27157, USA.
  • Sexton T; Center for the Neurobiology of Addiction Treatment, Department of Physiology and Pharmacology, Wake Forest School of Medicine, Medical Center Blvd., Winston-Salem, NC 27157, USA.
  • Beveridge TJR; Center for the Neurobiology of Addiction Treatment, Department of Physiology and Pharmacology, Wake Forest School of Medicine, Medical Center Blvd., Winston-Salem, NC 27157, USA.
  • Smith HR; Center for the Neurobiology of Addiction Treatment, Department of Physiology and Pharmacology, Wake Forest School of Medicine, Medical Center Blvd., Winston-Salem, NC 27157, USA.
  • Miller MD; Center for the Neurobiology of Addiction Treatment, Department of Physiology and Pharmacology, Wake Forest School of Medicine, Medical Center Blvd., Winston-Salem, NC 27157, USA.
  • Blough BE; Center for Drug Discovery, RTI International, Research Triangle Park, NC 27709, USA.
  • Porrino LJ; Center for the Neurobiology of Addiction Treatment, Department of Physiology and Pharmacology, Wake Forest School of Medicine, Medical Center Blvd., Winston-Salem, NC 27157, USA.
  • Childers SR; Center for the Neurobiology of Addiction Treatment, Department of Physiology and Pharmacology, Wake Forest School of Medicine, Medical Center Blvd., Winston-Salem, NC 27157, USA.
  • Howlett AC; Center for the Neurobiology of Addiction Treatment, Department of Physiology and Pharmacology, Wake Forest School of Medicine, Medical Center Blvd., Winston-Salem, NC 27157, USA. Electronic address: ahowlett@wakehealth.edu.
Brain Res ; 1761: 147387, 2021 Feb 23.
Article en En | MEDLINE | ID: mdl-33631209

Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: Brain Res Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: Brain Res Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos