Corneal cross-linking for treatment of progressive keratoconus in a patient with Alport syndrome: A case report.
Eur J Ophthalmol
; 31(4): 1584-1587, 2021 Jul.
Article
en En
| MEDLINE
| ID: mdl-33631984
ABSTRACT
PURPOSE:
Ocular features of Alport syndrome include anterior lenticonus, posterior polymorphous corneal dystrophy, and fleck-and-dot retinopathy in most cases. Keratoconus in such patients has been rarely mentioned in previous studies. To our knowledge, this is the first report of corneal cross-linking for halting the progression of keratoconus in a patient with Alport syndrome. CASE REPORT A 22-year-old male was referred for his initial corneal topography, after he was already prescribed with rigid gas-permeable contact lenses. Alport syndrome was diagnosed in his infancy and gene COL4A5 mutation was confirmed. Ophthalmological evaluation confirmed keratoconus. One-year follow-up showed a progression on his right eye and standard corneal cross-linking was performed. Stabilization of the disease marked by normalization in visual function and corneal tomography values was noticed 1 year after the procedure.CONCLUSIONS:
When diagnosing ocular clinical findings of Alport syndrome, keratoconus should be considered. Standard corneal cross-linking protocol can halt its progression.Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Fotoquimioterapia
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Distrofias Hereditarias de la Córnea
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Queratocono
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Nefritis Hereditaria
Tipo de estudio:
Diagnostic_studies
/
Guideline
Límite:
Adult
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Humans
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Male
Idioma:
En
Revista:
Eur J Ophthalmol
Asunto de la revista:
OFTALMOLOGIA
Año:
2021
Tipo del documento:
Article
País de afiliación:
Croacia