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Cyclosporine modulates neutrophil functions via the SIRT6-HIF-1α-glycolysis axis to alleviate severe ulcerative colitis.
Lu, Huiying; Lin, Jian; Xu, Chunjin; Sun, Mingming; Zuo, Keqiang; Zhang, Xiaoping; Li, Mingsong; Huang, Hailiang; Li, Zhong; Wu, Wei; Feng, Baisui; Liu, Zhanju.
Afiliación
  • Lu H; Center for IBD Research, Department of Gastroenterology, Shanghai Tenth People's Hospital of Tongji University, Shanghai, China.
  • Lin J; Center for IBD Research, Department of Gastroenterology, Shanghai Tenth People's Hospital of Tongji University, Shanghai, China.
  • Xu C; Department of Gastroenterology, First People's Hospital of Shangqiu City Affiliated to Xinxiang Medical University, Shangqiu, China.
  • Sun M; Center for IBD Research, Department of Gastroenterology, Shanghai Tenth People's Hospital of Tongji University, Shanghai, China.
  • Zuo K; Center for IBD Research, Department of Gastroenterology, Shanghai Tenth People's Hospital of Tongji University, Shanghai, China.
  • Zhang X; Center for IBD Research, Department of Gastroenterology, Shanghai Tenth People's Hospital of Tongji University, Shanghai, China.
  • Li M; Department of Gastroenterology, Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
  • Huang H; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.
  • Li Z; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.
  • Wu W; Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.
  • Feng B; Shanghai Cell Therapy Group, Shanghai, China.
  • Liu Z; Center for IBD Research, Department of Gastroenterology, Shanghai Tenth People's Hospital of Tongji University, Shanghai, China.
Clin Transl Med ; 11(2): e334, 2021 02.
Article en En | MEDLINE | ID: mdl-33634990
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Colitis Ulcerosa / Ciclosporina / Sirtuinas / Subunidad alfa del Factor 1 Inducible por Hipoxia / Glucólisis / Inmunosupresores / Neutrófilos Límite: Adult / Aged / Humans / Male / Middle aged Idioma: En Revista: Clin Transl Med Año: 2021 Tipo del documento: Article País de afiliación: China
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Colitis Ulcerosa / Ciclosporina / Sirtuinas / Subunidad alfa del Factor 1 Inducible por Hipoxia / Glucólisis / Inmunosupresores / Neutrófilos Límite: Adult / Aged / Humans / Male / Middle aged Idioma: En Revista: Clin Transl Med Año: 2021 Tipo del documento: Article País de afiliación: China