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mTORC1-chaperonin CCT signaling regulates m6A RNA methylation to suppress autophagy.
Tang, Hong-Wen; Weng, Jui-Hsia; Lee, Wen Xing; Hu, Yanhui; Gu, Lei; Cho, Sungyun; Lee, Gina; Binari, Richard; Li, Cathleen; Cheng, Min En; Kim, Ah-Ram; Xu, Jun; Shen, Zhangfei; Xu, Chiwei; Asara, John M; Blenis, John; Perrimon, Norbert.
Afiliación
  • Tang HW; Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore 169857, Singapore; hongwen.tang@duke-nus.edu.sg perrimon@receptor.med.harvard.edu.
  • Weng JH; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115.
  • Lee WX; Department of Systems Biology, Harvard Medical School, Boston, MA 02115.
  • Hu Y; Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore 169857, Singapore.
  • Gu L; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115.
  • Cho S; Division of Newborn Medicine and Epigenetics Program, Department of Medicine, Boston Children's Hospital, Boston, MA 02115.
  • Lee G; Department of Cell Biology, Harvard Medical School, Boston, MA 02115.
  • Binari R; Max Planck Institute for Heart and Lung Research, 61231 Bad Nauheim, Germany.
  • Li C; Department of Pharmacology, Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065.
  • Cheng ME; Department of Pharmacology, Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065.
  • Kim AR; Department of Microbiology and Molecular Genetics, Chao Family Comprehensive Cancer Center, University of California Irvine School of Medicine, Irvine, CA 92697.
  • Xu J; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115.
  • Shen Z; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115.
  • Xu C; Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore 169857, Singapore.
  • Asara JM; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115.
  • Blenis J; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115.
  • Perrimon N; Division of Newborn Medicine and Epigenetics Program, Department of Medicine, Boston Children's Hospital, Boston, MA 02115.
Proc Natl Acad Sci U S A ; 118(10)2021 03 09.
Article en En | MEDLINE | ID: mdl-33649236
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Proteínas Represoras / Autofagia / Transducción de Señal / Receptores Citoplasmáticos y Nucleares / Proteínas de Drosophila / Diana Mecanicista del Complejo 1 de la Rapamicina / Metiltransferasas Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2021 Tipo del documento: Article
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Proteínas Represoras / Autofagia / Transducción de Señal / Receptores Citoplasmáticos y Nucleares / Proteínas de Drosophila / Diana Mecanicista del Complejo 1 de la Rapamicina / Metiltransferasas Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2021 Tipo del documento: Article