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Inhibition of neuroinflammatory nitric oxide signaling suppresses glycation and prevents neuronal dysfunction in mouse prion disease.
Bourgognon, Julie-Myrtille; Spiers, Jereme G; Robinson, Sue W; Scheiblich, Hannah; Glynn, Paul; Ortori, Catharine; Bradley, Sophie J; Tobin, Andrew B; Steinert, Joern R.
Afiliación
  • Bourgognon JM; Centre for Immunobiology, University of Glasgow, Glasgow, G12 8TA, United Kingdom.
  • Spiers JG; Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, VIC 3083, Melbourne, Australia.
  • Robinson SW; Medical Research Council Toxicology Unit, University of Leicester, Leicester, LE1 9HN, United Kingdom.
  • Scheiblich H; Department of Neurodegenerative Disease and Geriatric Psychiatry/Neurology, University of Bonn, Bonn 53127, Germany.
  • Glynn P; Medical Research Council Toxicology Unit, University of Leicester, Leicester, LE1 9HN, United Kingdom.
  • Ortori C; School of Pharmacy, University of Nottingham, Nottingham NG7 2RD, United Kingdom.
  • Bradley SJ; Centre for Translational Pharmacology, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8QQ, United Kingdom.
  • Tobin AB; Centre for Translational Pharmacology, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8QQ, United Kingdom.
  • Steinert JR; School of Life Sciences, Queen's Medical Centre, University of Nottingham, Nottingham, NG7 2UH, United Kingdom joern.steinert@nottingham.ac.uk.
Proc Natl Acad Sci U S A ; 118(10)2021 03 09.
Article en En | MEDLINE | ID: mdl-33653950
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Transducción de Señal / Enfermedades por Prión / Región CA1 Hipocampal / Neuronas / Óxido Nítrico Límite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Transducción de Señal / Enfermedades por Prión / Región CA1 Hipocampal / Neuronas / Óxido Nítrico Límite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido