LIMK1 nuclear translocation promotes hepatocellular carcinoma progression by increasing p-ERK nuclear shuttling and by activating c-Myc signalling upon EGF stimulation.

Pan, Zhihua; Liu, Chaoqun; Zhi, Yunfei; Xie, Zhiyue; Wu, Ling; Jiang, Muhong; Zhang, Yujie; Zhou, Rui; Zhao, Liang

Pan, Zhihua; Liu, Chaoqun; Zhi, Yunfei; Xie, Zhiyue; Wu, Ling; Jiang, Muhong; Zhang, Yujie; Zhou, Rui; Zhao, Liang.

Afiliación

Pan Z; Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Liu C; Department of Pathology, Guangdong Province Key Laboratory of Molecular Tumor Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Zhi Y; Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Xie Z; Department of Pathology, Guangdong Province Key Laboratory of Molecular Tumor Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Wu L; Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Jiang M; Department of Pathology, Guangdong Province Key Laboratory of Molecular Tumor Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Zhang Y; Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Zhou R; Department of Pathology, Guangdong Province Key Laboratory of Molecular Tumor Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Zhao L; Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, China.

Oncogene ; 40(14): 2581-2595, 2021 04.

Article en En | MEDLINE | ID: mdl-33686242

Asunto(s)

Carcinoma Hepatocelular/genética; Factor de Crecimiento Epidérmico/metabolismo; Genes myc/genética; Quinasas Lim/metabolismo; Neoplasias Hepáticas/genética; Carcinoma Hepatocelular/patología; Progresión de la Enfermedad; Humanos; Neoplasias Hepáticas/patología

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Genes myc / Carcinoma Hepatocelular / Factor de Crecimiento Epidérmico / Quinasas Lim / Neoplasias Hepáticas Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Oncogene Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2021 Tipo del documento: Article País de afiliación: China

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