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KRAS/GNAS-testing by highly sensitive deep targeted next generation sequencing improves the endoscopic ultrasound-guided workup of suspected mucinous neoplasms of the pancreas.
Schmitz, Daniel; Kazdal, Daniel; Allgäuer, Michael; Trunk, Marcus; Vornhusen, Sylke; Nahm, Anna-Maria; Doll, Matthias; Weingärtner, Simon; Endris, Volker; Penzel, Roland; Kirchner, Martina; Brandt, Regine; Neumann, Olaf; Sültmann, Holger; Budczies, Jan; Kienle, Peter; Magdeburg, Richard; Hetjens, Svetlana; Schirmacher, Peter; Bergmann, Frank; Rudi, Jochen; Stenzinger, Albrecht; Volckmar, Anna-Lena.
Afiliación
  • Schmitz D; Department of Gastroenterology, Oncology and Diabetology, Theresienkrankenhaus and St. Hedwigsklinik, University of Heidelberg, Heidelberg, Germany.
  • Kazdal D; Institute of Pathology, University Hospital of Heidelberg, Heidelberg, Germany.
  • Allgäuer M; Institute of Pathology, University Hospital of Heidelberg, Heidelberg, Germany.
  • Trunk M; Institute of Pathology, SYNLAB GmbH Mannheim, Mannheim, Germany.
  • Vornhusen S; Institute of Pathology, SYNLAB GmbH Mannheim, Mannheim, Germany.
  • Nahm AM; Department of Gastroenterology, Oncology and Diabetology, Theresienkrankenhaus and St. Hedwigsklinik, University of Heidelberg, Heidelberg, Germany.
  • Doll M; Department of Gastroenterology, Oncology and Diabetology, Theresienkrankenhaus and St. Hedwigsklinik, University of Heidelberg, Heidelberg, Germany.
  • Weingärtner S; Department of Gastroenterology, Oncology and Diabetology, Theresienkrankenhaus and St. Hedwigsklinik, University of Heidelberg, Heidelberg, Germany.
  • Endris V; Institute of Pathology, University Hospital of Heidelberg, Heidelberg, Germany.
  • Penzel R; Institute of Pathology, University Hospital of Heidelberg, Heidelberg, Germany.
  • Kirchner M; Institute of Pathology, University Hospital of Heidelberg, Heidelberg, Germany.
  • Brandt R; Institute of Pathology, University Hospital of Heidelberg, Heidelberg, Germany.
  • Neumann O; Institute of Pathology, University Hospital of Heidelberg, Heidelberg, Germany.
  • Sültmann H; German Cancer Consortium (DKTK), Partner Site Heidelberg, and German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Budczies J; Institute of Pathology, University Hospital of Heidelberg, Heidelberg, Germany.
  • Kienle P; Department of General and Visceral Surgery, Theresienkrankenhaus and St. Hedwigsklinik, University of Heidelberg, Mannheim, Germany.
  • Magdeburg R; Department of General and Visceral Surgery, Theresienkrankenhaus and St. Hedwigsklinik, University of Heidelberg, Mannheim, Germany.
  • Hetjens S; Medical Statistics, Biomathematics and Information Processing of Mannheim University Hospital, University Hospital of Heidelberg, Mannheim, Germany.
  • Schirmacher P; Institute of Pathology, University Hospital of Heidelberg, Heidelberg, Germany.
  • Bergmann F; German Cancer Consortium (DKTK), Partner Site Heidelberg, and German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Rudi J; Institute of Pathology, University Hospital of Heidelberg, Heidelberg, Germany.
  • Stenzinger A; Department of Gastroenterology, Oncology and Diabetology, Theresienkrankenhaus and St. Hedwigsklinik, University of Heidelberg, Heidelberg, Germany.
  • Volckmar AL; Institute of Pathology, University Hospital of Heidelberg, Heidelberg, Germany.
Genes Chromosomes Cancer ; 60(7): 489-497, 2021 07.
Article en En | MEDLINE | ID: mdl-33686791

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Quiste Pancreático / Neoplasias Pancreáticas / Proteínas Proto-Oncogénicas p21(ras) / Cromograninas / Neoplasias Quísticas, Mucinosas y Serosas / Subunidades alfa de la Proteína de Unión al GTP Gs / Secuenciación de Nucleótidos de Alto Rendimiento / Biopsia por Aspiración con Aguja Fina Guiada por Ultrasonido Endoscópico Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Genes Chromosomes Cancer Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2021 Tipo del documento: Article País de afiliación: Alemania

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Quiste Pancreático / Neoplasias Pancreáticas / Proteínas Proto-Oncogénicas p21(ras) / Cromograninas / Neoplasias Quísticas, Mucinosas y Serosas / Subunidades alfa de la Proteína de Unión al GTP Gs / Secuenciación de Nucleótidos de Alto Rendimiento / Biopsia por Aspiración con Aguja Fina Guiada por Ultrasonido Endoscópico Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Genes Chromosomes Cancer Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2021 Tipo del documento: Article País de afiliación: Alemania