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Does adaptive thermogenesis occur after weight loss in adults? A systematic review.
Nunes, Catarina L; Casanova, Nuno; Francisco, Ruben; Bosy-Westphal, Anja; Hopkins, Mark; Sardinha, Luís B; Silva, Analiza M.
Afiliación
  • Nunes CL; Exercise and Health Laboratory, CIPER, Faculdade Motricidade Humana, Universidade de Lisboa, Estrada da Costa, Cruz-Quebrada 1499-002, Portugal.
  • Casanova N; School of Food Science and Nutrition, Faculty of Environment, University of Leeds, Leeds, UK.
  • Francisco R; Exercise and Health Laboratory, CIPER, Faculdade Motricidade Humana, Universidade de Lisboa, Estrada da Costa, Cruz-Quebrada 1499-002, Portugal.
  • Bosy-Westphal A; Department of Human Nutrition, Institute of Human Nutrition and Food Sciences, Christian-Albrechts University, Kiel, Germany.
  • Hopkins M; School of Food Science and Nutrition, Faculty of Environment, University of Leeds, Leeds, UK.
  • Sardinha LB; Exercise and Health Laboratory, CIPER, Faculdade Motricidade Humana, Universidade de Lisboa, Estrada da Costa, Cruz-Quebrada 1499-002, Portugal.
  • Silva AM; Exercise and Health Laboratory, CIPER, Faculdade Motricidade Humana, Universidade de Lisboa, Estrada da Costa, Cruz-Quebrada 1499-002, Portugal.
Br J Nutr ; 127(3): 451-469, 2022 02 14.
Article en En | MEDLINE | ID: mdl-33762040
ABSTRACT
Adaptive thermogenesis (AT) has been proposed to be a compensatory response that may resist weight loss (WL) and promote weight regain. This systematic review examined the existence of AT in adults after a period of negative energy balance (EB) with or without a weight stabilisation phase. Studies published until 15 May 2020 were identified from PubMed, Cochrane Library, EMBASE, MEDLINE, SCOPUS and Web of Science. Inclusion criteria included statistically significant WL, observational with follow-up or experimental studies, age > 18y, sample size ≥10 participants, intervention period ≥ 1week, published in English, objective measures of total daily energy expenditure (EE) (TDEE), resting EE (REE) and sleeping EE(SEE). The systematic review was registered at PROSPERO (2020 CRD42020165348). A total of thirty-three studies comprising 2528 participants were included. AT was observed in twenty-seven studies. Twenty-three studies showed significant values for AT for REE (82·8 %), four for TDEE (80·0 %) and two for SEE (100 %). A large heterogeneity in the methods used to quantify AT and between subjects and among studies regarding the magnitude of WL and/or of AT was reported. Well-designed studies reported lower or non-significant values for AT. These findings suggest that although WL may lead to AT in some of the EE components, these values may be small or non-statistically significant when higher-quality methodological designs are used. Furthermore, AT seems to be attenuated, or non-existent, after periods of weight stabilisation/neutral EB. More high-quality studies are warranted not only to disclose the existence of AT but also to understand its clinical implications on weight management outcomes.
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Termogénesis / Obesidad Tipo de estudio: Prognostic_studies / Systematic_reviews Límite: Adult / Humans Idioma: En Revista: Br J Nutr Año: 2022 Tipo del documento: Article País de afiliación: Portugal

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Termogénesis / Obesidad Tipo de estudio: Prognostic_studies / Systematic_reviews Límite: Adult / Humans Idioma: En Revista: Br J Nutr Año: 2022 Tipo del documento: Article País de afiliación: Portugal