Marginal Zone Lymphoma and Lung Adenocarcinoma with an EGFR Exon 19 E746-S752del Mutation in a Patient with IgG4-related Disease.
Intern Med
; 60(17): 2831-2837, 2021 Sep 01.
Article
en En
| MEDLINE
| ID: mdl-33775999
ABSTRACT
A 68-year-old man presented with a solid mass at the left renal pelvis and ureter with multiple systemic lymphadenopathies and a mass with a cavity in the right lower lobe of the lung. While a transbronchial lung biopsy revealed no malignancy, a biopsy of the renal pelvis showed marginal zone lymphoma with polyclonal IgG4-positive cells. The serum IgG4 level and presence of a bilateral orbital mass suggested Mikulicz disease. The lesions shrank following the administration of steroids. A rebiopsy confirmed lung adenocarcinoma, and its background showed IgG4-positive cells a year later. IgG4-related diseases require careful follow-up because they can be complicated by malignancy.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Linfoma de Células B de la Zona Marginal
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Adenocarcinoma del Pulmón
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Enfermedad Relacionada con Inmunoglobulina G4
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Neoplasias Pulmonares
Tipo de estudio:
Diagnostic_studies
Límite:
Aged
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Humans
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Male
Idioma:
En
Revista:
Intern Med
Asunto de la revista:
MEDICINA INTERNA
Año:
2021
Tipo del documento:
Article
País de afiliación:
Japón