First mitotic spindle formation is led by sperm centrosome-dependent MTOCs in humans.
Reproduction
; 161(5): V19-V22, 2021 05.
Article
en En
| MEDLINE
| ID: mdl-33843613
ABSTRACT
Unlike in mice, multinucleated blastomeres appear at a high frequency in the two-cell-stage embryos in humans. In this Point of View article, we demonstrate that the first mitotic spindle formation led by sperm centrosome-dependent microtubule organizing centers may cause a high incidence of zygotic division errors using human tripronuclear zygotes.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Espermatozoides
/
Cigoto
/
Centrosoma
/
Centro Organizador de los Microtúbulos
/
Huso Acromático
Límite:
Humans
/
Male
Idioma:
En
Revista:
Reproduction
Asunto de la revista:
MEDICINA REPRODUTIVA
Año:
2021
Tipo del documento:
Article
País de afiliación:
Japón