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The shared susceptibility epitope of HLA-DR4 binds citrullinated self-antigens and the TCR.
Lim, Jia Jia; Jones, Claerwen M; Loh, Tiing Jen; Ting, Yi Tian; Zareie, Pirooz; Loh, Khai L; Felix, Nathan J; Suri, Anish; McKinnon, Murray; Stevenaert, Frederik; Sharma, Ravi K; Klareskog, Lars; Malmström, Vivianne; Baker, Daniel G; Purcell, Anthony W; Reid, Hugh H; La Gruta, Nicole L; Rossjohn, Jamie.
Afiliación
  • Lim JJ; Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria 3800, Australia.
  • Jones CM; Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria 3800, Australia.
  • Loh TJ; Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria 3800, Australia.
  • Ting YT; Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria 3800, Australia.
  • Zareie P; Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria 3800, Australia.
  • Loh KL; Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria 3800, Australia.
  • Felix NJ; Janssen Research & Development LLC, Horsham, Philadelphia, PA, USA.
  • Suri A; Janssen Research & Development, Turnhoutseweg 30, BE-2340, Beerse, Belgium.
  • McKinnon M; Janssen Research & Development LLC, Horsham, Philadelphia, PA, USA.
  • Stevenaert F; Janssen Research & Development, Turnhoutseweg 30, BE-2340, Beerse, Belgium.
  • Sharma RK; Rheumatology Division, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, 17177 Stockholm, Sweden.
  • Klareskog L; Rheumatology Division, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, 17177 Stockholm, Sweden.
  • Malmström V; Rheumatology Division, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, 17177 Stockholm, Sweden.
  • Baker DG; Janssen Research & Development LLC, Horsham, Philadelphia, PA, USA.
  • Purcell AW; Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria 3800, Australia.
  • Reid HH; Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria 3800, Australia. hugh.reid@monash.edu nicole.la.gruta@monash.edu jamie.rossjohn@monash.edu.
  • La Gruta NL; Australian Research Council Centre of Excellence in Advanced Molecular Imaging, Monash University, Clayton, Victoria 3800, Australia.
  • Rossjohn J; Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria 3800, Australia. hugh.reid@monash.edu nicole.la.gruta@monash.edu jamie.rossjohn@monash.edu.
Sci Immunol ; 6(58)2021 04 16.
Article en En | MEDLINE | ID: mdl-33863750
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Artritis Reumatoide / Linfocitos T / Antígeno HLA-DR4 / Epítopos de Linfocito T Límite: Adult / Aged80 / Animals / Female / Humans / Male Idioma: En Revista: Sci Immunol Año: 2021 Tipo del documento: Article País de afiliación: Australia
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Artritis Reumatoide / Linfocitos T / Antígeno HLA-DR4 / Epítopos de Linfocito T Límite: Adult / Aged80 / Animals / Female / Humans / Male Idioma: En Revista: Sci Immunol Año: 2021 Tipo del documento: Article País de afiliación: Australia