Biased agonism in drug discovery: Is there a future for biased 5-HT<sub>1A</sub> receptor agonists in the treatment of neuropsychiatric diseases?

Salaciak, Kinga; Pytka, Karolina

Biased agonism in drug discovery: Is there a future for biased 5-HT_1A receptor agonists in the treatment of neuropsychiatric diseases?

Salaciak, Kinga; Pytka, Karolina.

Afiliación

Salaciak K; Department of Pharmacodynamics, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9, 30-688 Krakow, Poland.
Pytka K; Department of Pharmacodynamics, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9, 30-688 Krakow, Poland. Electronic address: karolina.pytka@uj.edu.pl.

Pharmacol Ther ; 227: 107872, 2021 11.

Article en En | MEDLINE | ID: mdl-33905796

Asunto(s)

Trastornos Mentales; Agonistas del Receptor de Serotonina 5-HT1; Descubrimiento de Drogas; Predicción; Humanos; Trastornos Mentales/tratamiento farmacológico; Agonistas del Receptor de Serotonina 5-HT1/farmacología

Palabras clave

5-HT(1A) receptor; Anxiety; Biased agonism; Depression; Memory

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Agonistas del Receptor de Serotonina 5-HT1 / Trastornos Mentales Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Humans Idioma: En Revista: Pharmacol Ther Año: 2021 Tipo del documento: Article País de afiliación: Polonia

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