Methadone overdose in patients following methadone mainte- nance treatment:A three years overview in the district of Bari (South-Italy).
Clin Ter
; 172(3): 247-249, 2021 May 05.
Article
en En
| MEDLINE
| ID: mdl-33956046
ABSTRACT
BACKGROUND:
Methadone maintenance treatment (MMT) is reco-gnized as a reference treatment for opioid dependence. According to Italian Law, at the beginning of the treatment patients must receive medication under the supervision of a physician, to avoid overdose. After a period of stability, patients could be allowed to take methadone at home in pre-arranged and personalized concentrations, in order to empower their self-responsibility. The aim of the present investigation is to underline the presence of a "glitch in the system" of the MMT.METHODS:
In the last three years, 7 forensic autopsies and toxi-cological analysis on corpses of regular opioid users were performed into the Institute of Legal Medicine of Bari.CONCLUSION:
Therefor an improvement of the MMT's guideline is needed to reduce methadone overdose deaths in future.RESULTS:
In all these cases very high methadone concentration in blood were found. All the 7 subjects were following a MMT in a Public Health Institute and the cause of death was respiratory depression by overdose of methadone in 6 cases.Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Tratamiento de Sustitución de Opiáceos
/
Metadona
/
Trastornos Relacionados con Opioides
Tipo de estudio:
Guideline
Límite:
Humans
País/Región como asunto:
Europa
Idioma:
En
Revista:
Clin Ter
Año:
2021
Tipo del documento:
Article
País de afiliación:
Italia