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Targeted truncation of the ADAM17 cytoplasmic domain in mice results in protein destabilization and a hypomorphic phenotype.
Lora, Jose; Weskamp, Gisela; Li, Thomas M; Maretzky, Thorsten; Shola, Dorjee T N; Monette, Sébastien; Lichtenthaler, Stefan F; Lu, Theresa T; Yang, Chingwen; Blobel, Carl P.
Afiliación
  • Lora J; Physiology, Biophysics and Systems Biology Program, Weill Cornell Medicine, New York, New York, USA; Arthritis and Tissue Degeneration Program, Hospital for Special Surgery, New York, New York, USA.
  • Weskamp G; Arthritis and Tissue Degeneration Program, Hospital for Special Surgery, New York, New York, USA.
  • Li TM; Autoimmunity and Inflammation Program, Hospital for Special Surgery, New York, New York, USA.
  • Maretzky T; Inflammation Program and Department of Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
  • Shola DTN; CRISPR and Genome Editing Resource Center, Rockefeller University, New York, New York, USA.
  • Monette S; Tri-Institutional Laboratory of Comparative Pathology, Sloan-Kettering Institute, New York, New York, USA.
  • Lichtenthaler SF; German Center for Neurodegenerative Diseases (DZNE), Technical University of Munich, Munich, Germany; Neuroproteomics, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Technical University of Munich, Munich
  • Lu TT; Autoimmunity and Inflammation Program, Hospital for Special Surgery, New York, New York, USA; Department of Microbiology and Immunology, Weill Cornell Medicine, New York, New York, USA.
  • Yang C; CRISPR and Genome Editing Resource Center, Rockefeller University, New York, New York, USA.
  • Blobel CP; Physiology, Biophysics and Systems Biology Program, Weill Cornell Medicine, New York, New York, USA; Arthritis and Tissue Degeneration Program, Hospital for Special Surgery, New York, New York, USA; Institute for Advanced Study, Technical University of Munich, Garching, Germany; Department of Medici
J Biol Chem ; 296: 100733, 2021.
Article en En | MEDLINE | ID: mdl-33957124
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Citoplasma / Proteína ADAM17 Límite: Animals Idioma: En Revista: J Biol Chem Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Citoplasma / Proteína ADAM17 Límite: Animals Idioma: En Revista: J Biol Chem Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos