The biological underpinnings of therapeutic resistance in pancreatic cancer.

Beatty, Gregory L; Werba, Gregor; Lyssiotis, Costas A; Simeone, Diane M

Beatty, Gregory L; Werba, Gregor; Lyssiotis, Costas A; Simeone, Diane M.

Afiliación

Beatty GL; Abramson Cancer Center; University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
Werba G; Division of Hematology-Oncology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
Lyssiotis CA; Department of Surgery, New York University School of Medicine, New York, New York 10016, USA.
Simeone DM; Perlmutter Cancer Center, New York University Langone Medical Center, New York, New York 10016, USA.

Genes Dev ; 35(13-14): 940-962, 2021 07 01.

Article en En | MEDLINE | ID: mdl-34117095

Asunto(s)

Carcinoma Ductal Pancreático; Neoplasias Pancreáticas; Carcinoma Ductal Pancreático/tratamiento farmacológico; Carcinoma Ductal Pancreático/genética; Carcinoma Ductal Pancreático/patología; Resistencia a Antineoplásicos/genética; Humanos; Terapia Molecular Dirigida/efectos adversos; Neoplasias Pancreáticas/tratamiento farmacológico; Neoplasias Pancreáticas/genética; Microambiente Tumoral

Palabras clave

PDAC; genetics; metabolism; microbiome; pancreatic cancer; pancreatic tumor microenvironment; targeted therapy; therapeutic resistance

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Carcinoma Ductal Pancreático Límite: Humans Idioma: En Revista: Genes Dev Asunto de la revista: BIOLOGIA MOLECULAR Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos

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