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The HCK/BTK inhibitor KIN-8194 is active in MYD88-driven lymphomas and overcomes mutated BTKCys481 ibrutinib resistance.
Yang, Guang; Wang, Jinhua; Tan, Li; Munshi, Manit; Liu, Xia; Kofides, Amanda; Chen, Jiaji G; Tsakmaklis, Nicholas; Demos, Maria G; Guerrera, Maria Luisa; Xu, Lian; Hunter, Zachary R; Che, Jinwei; Patterson, Christopher J; Meid, Kirsten; Castillo, Jorge J; Munshi, Nikhil C; Anderson, Kenneth C; Cameron, Michael; Buhrlage, Sara J; Gray, Nathanael S; Treon, Steven P.
Afiliación
  • Yang G; Bing Center for Waldenstrom's Macroglobulinemia.
  • Wang J; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA.
  • Tan L; Department of Cancer Biology, Dana-Farber Cancer Institute, and Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA.
  • Munshi M; Department of Cancer Biology, Dana-Farber Cancer Institute, and Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA.
  • Liu X; Bing Center for Waldenstrom's Macroglobulinemia.
  • Kofides A; Bing Center for Waldenstrom's Macroglobulinemia.
  • Chen JG; Bing Center for Waldenstrom's Macroglobulinemia.
  • Tsakmaklis N; Bing Center for Waldenstrom's Macroglobulinemia.
  • Demos MG; Bing Center for Waldenstrom's Macroglobulinemia.
  • Guerrera ML; Bing Center for Waldenstrom's Macroglobulinemia.
  • Xu L; Bing Center for Waldenstrom's Macroglobulinemia.
  • Hunter ZR; Bing Center for Waldenstrom's Macroglobulinemia.
  • Che J; Bing Center for Waldenstrom's Macroglobulinemia.
  • Patterson CJ; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA.
  • Meid K; Department of Cancer Biology, Dana-Farber Cancer Institute, and Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA.
  • Castillo JJ; Bing Center for Waldenstrom's Macroglobulinemia.
  • Munshi NC; Bing Center for Waldenstrom's Macroglobulinemia.
  • Anderson KC; Bing Center for Waldenstrom's Macroglobulinemia.
  • Cameron M; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA.
  • Buhrlage SJ; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA.
  • Gray NS; Jerome Lipper Multiple Myeloma Center, Dana-Farber Cancer Institute, Boston, MA; and.
  • Treon SP; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA.
Blood ; 138(20): 1966-1979, 2021 11 18.
Article en En | MEDLINE | ID: mdl-34132782
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Piperidinas / Adenina / Inhibidores de Proteínas Quinasas / Proteínas Proto-Oncogénicas c-hck / Factor 88 de Diferenciación Mieloide / Agammaglobulinemia Tirosina Quinasa / Linfoma Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Blood Año: 2021 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Piperidinas / Adenina / Inhibidores de Proteínas Quinasas / Proteínas Proto-Oncogénicas c-hck / Factor 88 de Diferenciación Mieloide / Agammaglobulinemia Tirosina Quinasa / Linfoma Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Blood Año: 2021 Tipo del documento: Article