Dependence on hypnotics: a comparative study between chronic users of benzodiazepines and Z-drugs.
Braz J Psychiatry
; 44(3): 248-256, 2022.
Article
en En
| MEDLINE
| ID: mdl-34133689
ABSTRACT
OBJECTIVE:
To evaluate dependence among chronic benzodiazepine and Z-drug users in Brazil.METHODS:
Chronic users of benzodiazepines (n=94), Z-drugs (n=74), or both (n=11) were recruited from the community, underwent a psychiatric evaluation and completed self-report instruments on hypnotic dependence, insomnia, anxiety, and depression. Users of benzodiazepines and Z-drugs were compared using t-tests, and logistic regression models were employed to explore significant predictors of a dependence diagnosis.RESULTS:
There was no difference in the prevalence of dependence among benzodiazepine (77.2%) and Z-drug (69.4%) users. Benzodiazepine users reported increased psychosocial aspects of dependence, anxiety, and depression. Preoccupation with the availability of medication (prevalence ratio [PR] = 2.39 [1.15-5.20]) and insomnia (PR = 1.10 [1.02-1.19]) were associated with a diagnosis of dependence (n=175).CONCLUSION:
The prevalence of dependence was similar among both drug classes. The increased self-reported dependence, anxiety, and depression among benzodiazepine users may be due to behavioral rather than pharmacological aspects of medication use. Behaviors related to hypnotic use were important predictors of dependence.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Trastornos Relacionados con Sustancias
/
Trastornos del Inicio y del Mantenimiento del Sueño
Tipo de estudio:
Prognostic_studies
/
Risk_factors_studies
Límite:
Humans
Idioma:
En
Revista:
Braz J Psychiatry
Asunto de la revista:
PSIQUIATRIA
Año:
2022
Tipo del documento:
Article
País de afiliación:
Brasil