Cisplatin induces differentiation in teratomas derived from pluripotent stem cells.

Kurata, Atsushi; Takanashi, Masakatsu; Ohno, Shin-Ichiro; Fujita, Koji; Kuroda, Masahiko

Kurata, Atsushi; Takanashi, Masakatsu; Ohno, Shin-Ichiro; Fujita, Koji; Kuroda, Masahiko.

Afiliación

Kurata A; Department of Molecular Pathology, Tokyo Medical University, 6-1-1, Shinjuku, Shinjuku-ku, Tokyo, Japan.
Takanashi M; Department of Molecular Pathology, Tokyo Medical University, 6-1-1, Shinjuku, Shinjuku-ku, Tokyo, Japan.
Ohno SI; Department of Molecular Pathology, Tokyo Medical University, 6-1-1, Shinjuku, Shinjuku-ku, Tokyo, Japan.
Fujita K; Department of Molecular Pathology, Tokyo Medical University, 6-1-1, Shinjuku, Shinjuku-ku, Tokyo, Japan.
Kuroda M; Department of Molecular Pathology, Tokyo Medical University, 6-1-1, Shinjuku, Shinjuku-ku, Tokyo, Japan.

Regen Ther ; 18: 117-126, 2021 Dec.

Article en En | MEDLINE | ID: mdl-34141836

Palabras clave

ALP, alkaline phosphatase; ATP4B, ATPase H+/K+ transporting beta subunit; CR, chemotherapeutic retroconversion; Cisplatin; DMEM, Dulbecco's modified Eagle's medium; Differentiation; ESC, embryonic stem cell; Embryonic stem cells; FCS, fetal calf serum; HE, hematoxylin and eosin; Immature teratoma; Induced pluripotent stem cells; KSR, knockout serum replacement; LIF, leukemia inhibitory factor; MEF, mouse embryonic fibroblast; PBS, phosphate buffered saline; PCNA, proliferating cell nuclear antigen; RAG, recombination activating gene; RLU, relative light units; RT, room temperature; iPSC, induced pluripotent stem cell; ssDNA, single stranded DNA; α-SMA, α-smooth muscle actin

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Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: Regen Ther Año: 2021 Tipo del documento: Article País de afiliación: Japón

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Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: Regen Ther Año: 2021 Tipo del documento: Article País de afiliación: Japón