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Modeling Phenotypic Heterogeneity of Glycogen Storage Disease Type 1a Liver Disease in Mice by Somatic CRISPR/CRISPR-associated protein 9-Mediated Gene Editing.
Rutten, Martijn G S; Derks, Terry G J; Huijkman, Nicolette C A; Bos, Trijnie; Kloosterhuis, Niels J; van de Kolk, Kees C W A; Wolters, Justina C; Koster, Mirjam H; Bongiovanni, Laura; Thomas, Rachel E; de Bruin, Alain; van de Sluis, Bart; Oosterveer, Maaike H.
Afiliación
  • Rutten MGS; Department of Pediatrics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
  • Derks TGJ; Section of Metabolic Diseases, Beatrix Children's Hospital, University Medical Center Groningen, Groningen, The Netherlands.
  • Huijkman NCA; Department of Pediatrics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
  • Bos T; Department of Laboratory Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
  • Kloosterhuis NJ; Department of Pediatrics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
  • van de Kolk KCWA; Central Animal Facility, Groningen Small Animal Imaging Facility (Gronsai), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
  • Wolters JC; Department of Pediatrics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
  • Koster MH; Department of Pediatrics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
  • Bongiovanni L; Dutch Molecular Pathology Center, Faculty of Veterinary Medicine, Utrecht University, CL Utrecht, The Netherlands.
  • Thomas RE; Dutch Molecular Pathology Center, Faculty of Veterinary Medicine, Utrecht University, CL Utrecht, The Netherlands.
  • de Bruin A; Department of Pediatrics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
  • van de Sluis B; Dutch Molecular Pathology Center, Faculty of Veterinary Medicine, Utrecht University, CL Utrecht, The Netherlands.
  • Oosterveer MH; Department of Pediatrics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Hepatology ; 74(5): 2491-2507, 2021 11.
Article en En | MEDLINE | ID: mdl-34157136
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Fenotipo / Enfermedad del Almacenamiento de Glucógeno Tipo I / Heterogeneidad Genética / Modelos Animales de Enfermedad / Repeticiones Palindrómicas Cortas Agrupadas y Regularmente Espaciadas / Edición Génica / Proteína 9 Asociada a CRISPR Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals Idioma: En Revista: Hepatology Año: 2021 Tipo del documento: Article País de afiliación: Países Bajos
Texto completo
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XML
PubMed Links
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Fenotipo / Enfermedad del Almacenamiento de Glucógeno Tipo I / Heterogeneidad Genética / Modelos Animales de Enfermedad / Repeticiones Palindrómicas Cortas Agrupadas y Regularmente Espaciadas / Edición Génica / Proteína 9 Asociada a CRISPR Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals Idioma: En Revista: Hepatology Año: 2021 Tipo del documento: Article País de afiliación: Países Bajos