Inhibiting Eukaryotic Elongation Factor 2 Kinase: An Update on Pharmacological Small-Molecule Compounds in Cancer.

Zhu, Shiou; Liao, Minru; Tan, Huidan; Zhu, Lingjuan; Chen, Yi; He, Gu; Liu, Bo

Zhu, Shiou; Liao, Minru; Tan, Huidan; Zhu, Lingjuan; Chen, Yi; He, Gu; Liu, Bo.

Afiliación

Zhu S; State Key Laboratory of Biotherapy and Cancer Center and Department of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu 610041, China.
Liao M; State Key Laboratory of Biotherapy and Cancer Center and Department of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu 610041, China.
Tan H; State Key Laboratory of Biotherapy and Cancer Center and Department of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu 610041, China.
Zhu L; State Key Laboratory of Biotherapy and Cancer Center and Department of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu 610041, China.
Chen Y; State Key Laboratory of Biotherapy and Cancer Center and Department of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu 610041, China.
He G; State Key Laboratory of Biotherapy and Cancer Center and Department of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu 610041, China.
Liu B; State Key Laboratory of Biotherapy and Cancer Center and Department of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu 610041, China.

J Med Chem ; 64(13): 8870-8883, 2021 07 08.

Article en En | MEDLINE | ID: mdl-34162208

Asunto(s)

Antineoplásicos/farmacología; Quinasa del Factor 2 de Elongación/antagonistas & inhibidores; Neoplasias/tratamiento farmacológico; Inhibidores de Proteínas Quinasas/farmacología; Bibliotecas de Moléculas Pequeñas/farmacología; Antineoplásicos/síntesis química; Antineoplásicos/química; Quinasa del Factor 2 de Elongación/metabolismo; Humanos; Modelos Moleculares; Estructura Molecular; Neoplasias/metabolismo; Inhibidores de Proteínas Quinasas/síntesis química; Inhibidores de Proteínas Quinasas/química; Bibliotecas de Moléculas Pequeñas/síntesis química; Bibliotecas de Moléculas Pequeñas/química

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Inhibidores de Proteínas Quinasas / Quinasa del Factor 2 de Elongación / Bibliotecas de Moléculas Pequeñas / Neoplasias / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2021 Tipo del documento: Article País de afiliación: China

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