NK Cells in Chronic Lymphocytic Leukemia and Their Therapeutic Implications.

Sportoletti, Paolo; De Falco, Filomena; Del Papa, Beatrice; Baldoni, Stefano; Guarente, Valerio; Marra, Andrea; Dorillo, Erica; Rompietti, Chiara; Adamo, Francesco Maria; Ruggeri, Loredana; Di Ianni, Mauro; Rosati, Emanuela

Sportoletti, Paolo; De Falco, Filomena; Del Papa, Beatrice; Baldoni, Stefano; Guarente, Valerio; Marra, Andrea; Dorillo, Erica; Rompietti, Chiara; Adamo, Francesco Maria; Ruggeri, Loredana; Di Ianni, Mauro; Rosati, Emanuela.

Afiliación

Sportoletti P; Centro di Ricerca Emato-Oncologica (CREO), Department of Medicine and Surgery, Institute of Hematology, University of Perugia, 06129 Perugia, Italy.
De Falco F; Centro di Ricerca Emato-Oncologica (CREO), Department of Medicine and Surgery, Institute of Hematology, University of Perugia, 06129 Perugia, Italy.
Del Papa B; Centro di Ricerca Emato-Oncologica (CREO), Department of Medicine and Surgery, Institute of Hematology, University of Perugia, 06129 Perugia, Italy.
Baldoni S; Centro di Ricerca Emato-Oncologica (CREO), Department of Medicine and Surgery, Institute of Hematology, University of Perugia, 06129 Perugia, Italy.
Guarente V; Department of Medicine and Sciences of Aging, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.
Marra A; Centro di Ricerca Emato-Oncologica (CREO), Department of Medicine and Surgery, Institute of Hematology, University of Perugia, 06129 Perugia, Italy.
Dorillo E; Centro di Ricerca Emato-Oncologica (CREO), Department of Medicine and Surgery, Institute of Hematology, University of Perugia, 06129 Perugia, Italy.
Rompietti C; Centro di Ricerca Emato-Oncologica (CREO), Department of Medicine and Surgery, Institute of Hematology, University of Perugia, 06129 Perugia, Italy.
Adamo FM; Centro di Ricerca Emato-Oncologica (CREO), Department of Medicine and Surgery, Institute of Hematology, University of Perugia, 06129 Perugia, Italy.
Ruggeri L; Centro di Ricerca Emato-Oncologica (CREO), Department of Medicine and Surgery, Institute of Hematology, University of Perugia, 06129 Perugia, Italy.
Di Ianni M; Centro di Ricerca Emato-Oncologica (CREO), Department of Medicine and Surgery, Institute of Hematology, University of Perugia, 06129 Perugia, Italy.
Rosati E; Department of Medicine and Sciences of Aging, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.

Int J Mol Sci ; 22(13)2021 Jun 22.

Article en En | MEDLINE | ID: mdl-34206399

Asunto(s)

Susceptibilidad a Enfermedades; Células Asesinas Naturales/inmunología; Células Asesinas Naturales/metabolismo; Leucemia Linfocítica Crónica de Células B/etiología; Leucemia Linfocítica Crónica de Células B/metabolismo; Biomarcadores; Comunicación Celular; Manejo de la Enfermedad; Humanos; Sistema Inmunológico/inmunología; Sistema Inmunológico/metabolismo; Inmunoterapia/efectos adversos; Inmunoterapia/métodos; Leucemia Linfocítica Crónica de Células B/diagnóstico; Leucemia Linfocítica Crónica de Células B/terapia; Ligandos; Unión Proteica; Receptores de Células Asesinas Naturales/genética; Receptores de Células Asesinas Naturales/metabolismo; Resultado del Tratamiento; Escape del Tumor/genética; Escape del Tumor/inmunología

Palabras clave

CLL immune evasion; NK cell alterations; NK cell receptors; NK cell-based immunotherapy; NK cells; chronic lymphocytic leukemia

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Células Asesinas Naturales / Leucemia Linfocítica Crónica de Células B / Susceptibilidad a Enfermedades Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Int J Mol Sci Año: 2021 Tipo del documento: Article País de afiliación: Italia

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