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ABCB1 and ABCG2 Together Limit the Distribution of ABCB1/ABCG2 Substrates to the Human Retina and the ABCG2 Single Nucleotide Polymorphism Q141K (c.421C> A) May Lead to Increased Drug Exposure.
El Biali, Myriam; Karch, Rudolf; Philippe, Cécile; Haslacher, Helmuth; Tournier, Nicolas; Hacker, Marcus; Zeitlinger, Markus; Schmidl, Doreen; Langer, Oliver; Bauer, Martin.
Afiliación
  • El Biali M; Department of Clinical Pharmacology, Medical University of Vienna, Vienna, VIE, Austria.
  • Karch R; Centre for Medical Statistics, Informatics, and Intelligent Systems, Medical University of Vienna, Vienna, VIE, Austria.
  • Philippe C; Division of Nuclear Medicine, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, VIE, Austria.
  • Haslacher H; Department of Laboratory Medicine, Medical University of Vienna, Vienna, VIE, Austria.
  • Tournier N; Laboratoire d'Imagerie Biomédicale Multimodale (BioMaps), CEA, CNRS, Inserm, Service Hospitalier Frédéric Joliot, Université Paris-Saclay, Orsay, France.
  • Hacker M; Division of Nuclear Medicine, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, VIE, Austria.
  • Zeitlinger M; Department of Clinical Pharmacology, Medical University of Vienna, Vienna, VIE, Austria.
  • Schmidl D; Department of Clinical Pharmacology, Medical University of Vienna, Vienna, VIE, Austria.
  • Langer O; Department of Clinical Pharmacology, Medical University of Vienna, Vienna, VIE, Austria.
  • Bauer M; Division of Nuclear Medicine, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, VIE, Austria.
Front Pharmacol ; 12: 698966, 2021.
Article en En | MEDLINE | ID: mdl-34220523

Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: Front Pharmacol Año: 2021 Tipo del documento: Article País de afiliación: Austria

Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: Front Pharmacol Año: 2021 Tipo del documento: Article País de afiliación: Austria