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Inhibition of Rag GTPase signaling in mice suppresses B cell responses and lymphomagenesis with minimal detrimental trade-offs.
Ortega-Molina, Ana; Lebrero-Fernández, Cristina; Sanz, Alba; Deleyto-Seldas, Nerea; Plata-Gómez, Ana Belén; Menéndez, Camino; Graña-Castro, Osvaldo; Caleiras, Eduardo; Efeyan, Alejo.
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  • Ortega-Molina A; Metabolism and Cell Signaling Laboratory, Spanish National Cancer Research Centre (CNIO), Melchor Fernandez Almagro 3, Madrid 28029, Spain. Electronic address: aortegam@cnio.es.
  • Lebrero-Fernández C; Metabolism and Cell Signaling Laboratory, Spanish National Cancer Research Centre (CNIO), Melchor Fernandez Almagro 3, Madrid 28029, Spain.
  • Sanz A; Metabolism and Cell Signaling Laboratory, Spanish National Cancer Research Centre (CNIO), Melchor Fernandez Almagro 3, Madrid 28029, Spain.
  • Deleyto-Seldas N; Metabolism and Cell Signaling Laboratory, Spanish National Cancer Research Centre (CNIO), Melchor Fernandez Almagro 3, Madrid 28029, Spain.
  • Plata-Gómez AB; Metabolism and Cell Signaling Laboratory, Spanish National Cancer Research Centre (CNIO), Melchor Fernandez Almagro 3, Madrid 28029, Spain.
  • Menéndez C; Metabolism and Cell Signaling Laboratory, Spanish National Cancer Research Centre (CNIO), Melchor Fernandez Almagro 3, Madrid 28029, Spain.
  • Graña-Castro O; Bioinformatics Unit, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Caleiras E; Histopathology Unit, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Efeyan A; Metabolism and Cell Signaling Laboratory, Spanish National Cancer Research Centre (CNIO), Melchor Fernandez Almagro 3, Madrid 28029, Spain. Electronic address: aefeyan@cnio.es.
Cell Rep ; 36(2): 109372, 2021 07 13.
Article en En | MEDLINE | ID: mdl-34260908
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Linfocitos B / Transducción de Señal / Proteínas de Unión al GTP Monoméricas / Carcinogénesis / Linfoma Límite: Animals Idioma: En Revista: Cell Rep Año: 2021 Tipo del documento: Article
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Linfocitos B / Transducción de Señal / Proteínas de Unión al GTP Monoméricas / Carcinogénesis / Linfoma Límite: Animals Idioma: En Revista: Cell Rep Año: 2021 Tipo del documento: Article