[Circulating tumour DNA in the treatment of cancer].

ABSTRACT

Circulating tumour DNA analysis has a potential to improve multiple aspects of cancer management. This includes a) early cancer detection in asymptomatic individuals, b) identification of patients with residual disease after curative intended treatment, c) patient stratification in relation to treatment decisions like adjuvant therapy and intensity of radiological surveillance, d) monitoring treatment effect for optimised adaptive therapy, e) identification of actionable targets, and f) early recurrence detection. These points are summarised in this review.